AIMC Topic: Machine Learning

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Body movements as biomarkers: Machine Learning-based prediction of HPA axis reactivity to stress.

Psychoneuroendocrinology
Body movements and posture provide valuable insights into stress responses, yet their relationship with endocrine biomarkers of the stress response remains underexplored. This study investigates whether movement patterns during the Trier Social Stres...

Deep transfer learning radiomics combined with explainable machine learning for preoperative thymoma risk prediction based on CT.

European journal of radiology
OBJECTIVE: To develop and validate a computerized tomography (CT)‑based deep transfer learning radiomics model combined with explainable machine learning for preoperative risk prediction of thymoma.

Using Machine Learning to Match Clients and Therapy Providers: Evaluating Clinical Quality and Cost of Care.

Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research
OBJECTIVES: Matching clients in need of mental healthcare with providers who will deliver high quality treatment presents a substantial challenge. Machine learning models hold potential for predicting the best pairings from a multitude of data points...

Scaffold Hopping with Generative Reinforcement Learning.

Journal of chemical information and modeling
Scaffold hopping-the design of novel scaffolds for existing lead candidates-is a multifaceted and nontrivial task, for medicinal chemists and computational approaches alike. Generative reinforcement learning can iteratively optimize desirable propert...

AffiGrapher: Contrastive Heterogeneous Graph Learning with Aromatic Virtual Nodes for RNA-Small Molecule Binding Affinity Prediction.

Journal of chemical information and modeling
RNA molecules exhibit diverse structures and functions, making them promising drug targets. However, predicting RNA-small molecule binding affinity remains challenging due to limited experimental data and the structural variability introduced by mult...

Developing interpretable machine learning models to predict length of stay and disposition decision for adult patients in emergency departments.

BMJ health & care informatics
OBJECTIVE: Machine learning (ML) models have emerged as tools to predict length of stay (LOS) and disposition decision (DD) in emergency departments (EDs) to combat overcrowding. However, site-specific ML models are not transferable to different site...

Predictive modeling for early detection of refractory esophageal stricture following esophageal atresia surgery: insight from a machine learning study.

Pediatric surgery international
BACKGROUND: Refractory esophageal stricture (RES) presents a challenging complication after esophageal atresia (EA) repair. Earlier identification of patients with RES could help clinical decision-making. However, there are currently limited articles...

Prognostic predictions in psychosis: exploring the complementary role of machine learning models.

BMJ mental health
BACKGROUND: Predicting outcomes in schizophrenia spectrum disorders is challenging due to the variability of individual trajectories. While machine learning (ML) shows promise in outcome prediction, it has not yet been integrated into clinical practi...

Machine learning-based optimization of biogas and methane yields in UASB reactors for treating domestic wastewater.

Biodegradation
This study aimed to optimize biogas and methane production from Up-flow anaerobic sludge blanket reactors for treating domestic wastewater using advanced machine learning models-namely, eXtreme Gradient Boosting (XGBoost) and its hybridized form, XGB...

From laser-on time to lithotripsy duration: improving the prediction of lithotripsy duration with 'Kidney Stone Calculator' using artificial intelligence.

World journal of urology
INTRODUCTION: "Kidney Stone Calculator" (KSC) helps to plan flexible ureteroscopy, providing the stone volume (SV) and an estimated duration of laser lithotripsy (eLD). eLD is calculated from in vitro ablation rates and SV. KSC's accuracy has been de...