AIMC Topic: Machine Learning

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Identifying main finding sentences in clinical case reports.

Database : the journal of biological databases and curation
Clinical case reports are the 'eyewitness reports' of medicine and provide a valuable, unique, albeit noisy and underutilized type of evidence. Generally, a case report has a single main finding that represents the reason for writing up the report in...

PTML Modeling for Alzheimer's Disease: Design and Prediction of Virtual Multi-Target Inhibitors of GSK3B, HDAC1, and HDAC6.

Current topics in medicinal chemistry
BACKGROUND: Alzheimer's disease is characterized by a progressive pattern of cognitive and functional impairment, which ultimately leads to death. Computational approaches have played an important role in the context of drug discovery for anti-Alzhei...

Artificial Neural Networks in Computer-Aided Drug Design: An Overview of Recent Advances.

Advances in experimental medicine and biology
Computer-aided drug design (CADD) is the framework in which the huge amount of data accumulated by high-throughput experimental methods used in drug design is quantitatively studied. Its objectives include pattern recognition, biomarker identificatio...

Multivariate Data Analysis and Machine Learning for Prediction of MCI-to-AD Conversion.

Advances in experimental medicine and biology
There has always been a need for discovering efficient and dependable Alzheimer's disease (AD) diagnostic biomarkers. Like the majority of diseases, the earlier the diagnosis, the most effective the treatment. (Semi)-automated structural magnetic res...

Antibody Clustering Using a Machine Learning Pipeline that Fuses Genetic, Structural, and Physicochemical Properties.

Advances in experimental medicine and biology
Antibody V domain clustering is of paramount importance to a repertoire of immunology-related areas. Although several approaches have been proposed for antibody clustering, still no consensus has been reached. Numerous attempts use information from g...

Using Reduced Amino Acid Alphabet and Biological Properties to Analyze and Predict Animal Neurotoxin Protein.

Current drug metabolism
AIMS: Because of the high affinity of these animal neurotoxin proteins for some special target site, they were usually used as pharmacological tools and therapeutic agents in medicine to gain deep insights into the function of the nervous system.

A Machine Learning Approach to Identification of Unhealthy Drinking.

Journal of the American Board of Family Medicine : JABFM
INTRODUCTION: Unhealthy drinking is prevalent in the United States, and yet it is underidentified and undertreated. Identifying unhealthy drinkers can be time-consuming and uncomfortable for primary care providers. An automated rule for identificatio...

Location detection of key areas in medical images based on Haar-like fusion contour feature learning.

Technology and health care : official journal of the European Society for Engineering and Medicine
BACKGROUND: Key area location is an important content of medical image processing and an important detail of auxiliary medical diagnosis.