AIMC Topic: Macrophages, Alveolar

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Bioinformatics Approach to Identifying Molecular Targets of Isoliquiritigenin Affecting Chronic Obstructive Pulmonary Disease: A Machine Learning Pharmacology Study.

International journal of molecular sciences Apr 21, 2025
To identify the molecular targets and possible mechanisms of isoliquiritigenin (ISO) in affecting chronic obstructive pulmonary disease (COPD) by regulating the glycolysis and phagocytosis of alveolar macrophages (AM). Datasets GSE130928 and GSE13896...
Humans Machine Learning Pulmonary Disease, Chronic Obstructive Gene Expression Profiling Protein Interaction Maps Gene Regulatory Networks Glycolysis Computational Biology Databases, Genetic Phagocytosis Chalcones Macrophages, Alveolar
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[Role and mechanism of the NOD-like receptor 3 inflammasome in ventilator-induced lung injury in rats].

Zhonghua wei zhong bing ji jiu yi xue Oct 1, 2015
OBJECTIVE: To investigate the role and its mechanism of the NOD-like receptor 3 (NLRP3) inflammasome in alveolar macrophages in ventilator-induced lung injury (VILI) in rats.
Animals Male Respiration, Artificial Lung RNA, Messenger Rats Rats, Sprague-Dawley Carrier Proteins Tidal Volume Interleukin-1beta NF-kappa B NLR Family, Pyrin Domain-Containing 3 Protein Interleukin-18 Inflammasomes Random Allocation Bronchoalveolar Lavage Fluid Caspase 1 Macrophages, Alveolar Ventilator-Induced Lung Injury
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