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Macrophages, Alveolar

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[Role and mechanism of the NOD-like receptor 3 inflammasome in ventilator-induced lung injury in rats].

Zhonghua wei zhong bing ji jiu yi xue 27132445
OBJECTIVE: To investigate the role and its mechanism of the NOD-like receptor 3 (NLRP3) inflammasome in alveolar macrophages in ventilator-induced lung injury (VILI) in rats.
Animals Bronchoalveolar Lavage Fluid Carrier Proteins Caspase 1 Inflammasomes Interleukin-18 Interleukin-1beta Lung Macrophages, Alveolar Male NF-kappa B NLR Family, Pyrin Domain-Containing 3 Protein Random Allocation Rats Rats, Sprague-Dawley Respiration, Artificial RNA, Messenger Tidal Volume Ventilator-Induced Lung Injury
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Bioinformatics Approach to Identifying Molecular Targets of Isoliquiritigenin Affecting Chronic Obstructive Pulmonary Disease: A Machine Learning Pharmacology Study.

International journal of molecular sciences 40332792
To identify the molecular targets and possible mechanisms of isoliquiritigenin (ISO) in affecting chronic obstructive pulmonary disease (COPD) by regulating the glycolysis and phagocytosis of alveolar macrophages (AM). Datasets GSE130928 and GSE13896...
Chalcones Computational Biology Databases, Genetic Gene Expression Profiling Gene Regulatory Networks Glycolysis Humans Machine Learning Macrophages, Alveolar Phagocytosis Protein Interaction Maps Pulmonary Disease, Chronic Obstructive
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