AIMC Topic: Caspase 1

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Analysis of the Relationship Between and Cytokine Gene Expression in Hematological Malignancy: Leveraging Explained Artificial Intelligence and Machine Learning for Small Dataset Insights.

International journal of medical sciences Apr 13, 2025
This study measures expression of () and related cytokine genes in bone marrow mononuclear cells in patients with hematological malignancies, analyzing the relationship between them with an integrated framework of statistical analyses, machine learn...
Bayes Theorem Caspase 1 Middle Aged Gene Expression Regulation, Neoplastic NF-kappa B p50 Subunit Female Biomarkers, Tumor Hematologic Neoplasms Male Machine Learning Cytokines Artificial Intelligence Humans
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A morphology and secretome map of pyroptosis.

Molecular biology of the cell Apr 9, 2025
Pyroptosis represents one type of programmed cell death. It is a form of inflammatory cell death that is canonically defined by caspase-1 cleavage and Gasdermin-mediated membrane pore formation. Caspase-1 initiates the inflammatory response (through ...
Pyroptosis Humans Caspase 1 Leukocytes, Mononuclear Apoptosis Interleukin-1beta Phosphate-Binding Proteins Intracellular Signaling Peptides and Proteins Gasdermins Secretome
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Screening necroptosis genes influencing osteoarthritis development based on machine learning.

Scientific reports Mar 15, 2025
Machine learning can be applied to identify key genes associated with osteoarthritis (OA). This study aimed to explore the differential expression of necroptosis-related genes (NRGs) during the progression of OA, identify key gene modules strongly li...
Machine Learning Gene Expression Profiling Humans Gene Ontology Caspase 1 Necroptosis Transcriptome Osteoarthritis Gene Regulatory Networks
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[A giant step towards elucidating the function of proteins].

Medecine sciences : M/S Feb 16, 2021
Artificial Intelligence Algorithms Deep Learning Proteins Protein Structure, Tertiary Caspase 1 Crystallography Myoglobin Protein Folding Caspases X-Ray Diffraction
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[Role and mechanism of the NOD-like receptor 3 inflammasome in ventilator-induced lung injury in rats].

Zhonghua wei zhong bing ji jiu yi xue Oct 1, 2015
OBJECTIVE: To investigate the role and its mechanism of the NOD-like receptor 3 (NLRP3) inflammasome in alveolar macrophages in ventilator-induced lung injury (VILI) in rats.
Interleukin-1beta Lung Macrophages, Alveolar NF-kappa B RNA, Messenger Ventilator-Induced Lung Injury Carrier Proteins Rats Inflammasomes Bronchoalveolar Lavage Fluid Tidal Volume Rats, Sprague-Dawley Random Allocation Caspase 1 NLR Family, Pyrin Domain-Containing 3 Protein Male Animals Interleukin-18 Respiration, Artificial
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