Age-related Macular Degeneration (AMD) is an irreversible and chronic medical condition characterized by drusen, Choroidal Neovascularization (CNV) and Geographic Atrophy (GA). AMD is one of the major causes of visual loss among elderly people. It is...
BACKGROUND: To investigate machine learning methods, ranging from simpler interpretable techniques to complex (non-linear) "black-box" approaches, for automated diagnosis of Age-related Macular Degeneration (AMD).
Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists)
Sep 1, 2025
INTRODUCTION: Artificial intelligence (AI) systems for age-related macular degeneration (AMD) diagnosis abound but are not yet widely implemented. AI implementation is complex, requiring the involvement of multiple, diverse stakeholders including tec...
OBJECTIVES: To compare the effectiveness of expert-designed machine learning models and code-free automated machine learning (AutoML) models in classifying optical coherence tomography (OCT) images for detecting age-related macular degeneration (AMD)...
Photodiagnosis and photodynamic therapy
Jun 1, 2025
PURPOSE: This study aimed to establish and validate a prediction model based on machine learning methods and SHAP algorithm to predict response to anti-vascular endothelial growth factor (VEGF) therapy in neovascular age-related macular degeneration ...
Studies in health technology and informatics
May 15, 2025
Optical Coherence Tomography (OCT) has become an indispensable imaging modality in ophthalmology, providing high-resolution cross-sectional images of the retina. Accurate classification of OCT images is crucial for diagnosing retinal diseases such as...
Deep learning models hold significant promise for disease diagnosis but often lack transparency in their decision-making processes, limiting trust and hindering clinical adoption. This study introduces a novel multi-task learning framework to enhance...
Translational vision science & technology
Feb 3, 2025
PURPOSE: To evaluate the performance of various approaches of processing three-dimensional (3D) optical coherence tomography (OCT) images for deep learning models in predicting area and future growth rate of geographic atrophy (GA) lesions caused by ...
Age-related macular degeneration (AMD) is a progressive degenerative retinal disease and a leading cause of blindness in older adults worldwide. According to numerous studies, the number of affected individuals reached 196 million in 2020, with proje...
BACKGROUND: Age-related macular degeneration (AMD) is a major cause of irreversible visual impairment, with dry AMD being the most prevalent form. Programmed cell death of retinal pigment epithelium (RPE) cells is a central mechanism in the pathogene...
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