Deformable medical image registration plays a significant role in medical image analysis. With the advancement of deep neural networks, learning-based deformable registration methods have made great strides due to their ability to perform fast end-to...
Biophysical modeling, particularly involving partial differential equations (PDEs), offers significant potential for tailoring disease treatment protocols to individual patients. However, the inverse problem-solving aspect of these models presents a ...
Functional Magnetic Resonance Imaging (fMRI) is used for extracting blood oxygen signals from brain regions to map brain functional connectivity for brain disease prediction. Despite its effectiveness, fMRI has not been widely used: on the one hand, ...
Analyzing anatomic shapes of tissues and organs is pivotal for accurate disease diagnostics and clinical decision-making. One prominent disease that depends on anatomic shape analysis is osteoarthritis, which affects 30 million Americans. To advance ...
Computer methods and programs in biomedicine
Mar 15, 2025
BACKGROUND: Atrial fibrillation (AF) is the most common cardiac arrhythmia, affecting up to 2 % of the population. Catheter ablation is a promising treatment for AF, particularly for paroxysmal AF patients, but it often has high recurrence rates. Dev...
Geometric transformations have been widely used to augment the size of training images. Existing methods often assume a unimodal distribution of the underlying transformations between images, which limits their power when data with multimodal distrib...
Autism spectrum disorder (ASD) is a neurodevelopmental condition that affects a child's cognitive and social skills, often diagnosed only after symptoms appear around age 2. Leveraging MRI for early ASD detection can improve intervention outcomes. Th...
BACKGROUND: Magnetic Resonance (MR) imaging is the preferred modality for staging in rectal cancer; however, despite its exceptional soft tissue contrast, segmenting rectal tumors on MR images remains challenging due to the overlapping appearance of ...
Segmentation of the breast region in dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) is essential for the automatic measurement of breast density and the quantitative analysis of imaging findings. This study aims to compare various dee...
American journal of Alzheimer's disease and other dementias
Mar 14, 2025
White matter hyperintensity (WMH) is associated with cognitive impairment. In this study, 79 patients with WMH from hospital 1 were randomly divided into a training set (62 patients) and an internal validation set (17 patients). In addition, 29 WMH p...
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