The intracellular pH (pH) is critical for understanding various pathologies, including brain tumors. While conventional pH measurement through P-MRS suffers from low spatial resolution and long scan times, H-based APT-CEST imaging offers higher resol...
Deformable brain templates are an important tool in many neuroimaging analyses. Conditional templates (e.g., age-specific templates) have advantages over single population templates by enabling improved registration accuracy and capturing common proc...
Perfluorooctanoic acid (PFOA), a widely used industrial chemical, poses significant environmental and biological toxicity, particularly affecting reproductive health. This study aimed to integrate network toxicology, machine learning, and molecular d...
Percutaneous screw fixation technique in pelvic trauma surgery is an extremely challenging operation that typically requires a trial-and-error insertion process under the guidance of continuous intraoperative X-ray. This process can be simplified by ...
INTRODUCTION: Hip fractures, particularly among the elderly, impose a significant public health burden due to increased morbidity and mortality. Femoral neck fractures, commonly resulting from low-energy falls, can lead to severe complications such a...
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Jun 1, 2025
Most lung cancer (LC) patients are diagnosed at advanced stages due to the lack of effective screening tools. This multicenter study analyzes 1043 saliva samples (334 LC cases and 709 non-LC cases) using a novel high-throughput platform for metabolic...
According to the statistics of relevant data, stroke is a relatively common cerebrovascular disease, and its incidence rate is as high as 185/100,000 to 219/100,000. Continuous care can improve the quality of life of stroke patients and reduce the ra...
Cardiovascular diseases comprise a diverse array of disorders impacting the cardiac structure and vascular system and rank among the predominant factors contributing to mortality on a global scale. Every day, a significant number of individuals die f...
BACKGROUND: Large Language Models (LLMs) hold promise for clinical decision support, but their real-world performance varies. We compared three leading models (OpenAI's "o1" Large Reasoning Model (LRM), Anthropic's Claude-3.5-Sonnet, and Meta's Llama...
Blood pressure is a critical risk factor for cardiovascular diseases (CVDs), yet most adults do not monitor it frequently enough to prevent serious complications. This is in part because the traditional cuff-based method is inconvenient, uncomfortabl...
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