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Metal Nanoparticles

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Radial SERS acquisition on coffee ring for Serum-based breast cancer diagnosis through Multilayer Perceptron.

Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy
The coffee-ring effect, involving spontaneous solute separation, has demonstrated promising potential in the context of patient serum analysis. In this study, an approach leveraging the coffee-ring-based analyte redistribution was developed for spect...

Identification of Phosphodiesterase type 5 inhibitors (PDE5is) analogues using surface-enhanced Raman scattering and machine learning algorithm.

Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy
Phosphodiesterase type 5 inhibitors (PDE5is), primarily used for the treatment of erectile dysfunction, have been severely misused in recent years, posing a threat to public health and safety. This study developed a method that combines Surface-enhan...

Freeze-Thaw-Induced Patterning of Extracellular Vesicles with Artificial Intelligence for Breast Cancers Identifications.

Small (Weinheim an der Bergstrasse, Germany)
Extracellular vesicles (EVs) play a crucial role in the occurrence and progression of cancer. The efficient isolation and analysis of EVs for early cancer diagnosis and prognosis have gained significant attention. In this study, for the first time, a...

Labyrinthine Wrinkle-Patterned Fiber Sensors Based on a 3D Stress Complementary Strategy for Machine Learning-Enabled Medical Monitoring and Action Recognition.

Small (Weinheim an der Bergstrasse, Germany)
Fiber strain sensors show good application potential in the field of wearable smart fabrics and equipment because of their characteristics of easy deformation and weaving. However, the integration of fiber strain sensors with sensitive response, good...

Machine Learning-Assisted "Shrink-Restricted" SERS Strategy for Classification of Environmental Nanoplastic-Induced Cell Death.

Environmental science & technology
The biotoxicity of nanoplastics (NPs), especially from environmental sources, and "NPs carrier effect" are in the early stages of research. This study presents a machine learning-assisted "shrink-restricted" SERS strategy (SRSS) to monitor molecular ...

A machine-learning-integrated portable electrochemiluminescence sensing platform for the visualization and high-throughput immunoassays.

Talanta
Electrochemiluminescence (ECL)-based point-of-care testing (POCT) has the potential to facilitate the rapid identification of diseases, offering advantages such as high sensitivity, strong selectivity, and minimal background interference. However, as...

Advancing DNA Structural Analysis: A SERS Approach Free from Citrate Interference Combined with Machine Learning.

The journal of physical chemistry letters
Surface-enhanced Raman spectroscopy (SERS) has become an indispensable tool for biomolecular analysis, yet the detection of DNA signals remains hindered by spectral interference from citrate ions, which overlap with key DNA features. This study intro...

Kinetics, central composite design and artificial neural network modelling of ciprofloxacin antibiotic photodegradation using fabricated cobalt-doped zinc oxide nanoparticles.

Scientific reports
Cobalt-doped zinc oxide nanoparticles were fabricated and examined in this study as a potential photocatalyst for the antibiotic ciprofloxacin (CIPF) degradation when exposed to visible LED light. The Co-precipitation technique created Cobalt-doped z...

Trace detection of antibiotics in wastewater using tunable core-shell nanoparticles SERS substrate combined with machine learning algorithms.

Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy
Surface-enhanced Raman scattering (SERS) show great potential for rapid and highly sensitive detection of trace amounts of contamination from the environment in the surface aquatic ecosystem. The widespread use of antibiotics has resulted in serious ...

Differential Diagnosis of Urinary Cancers by Surface-Enhanced Raman Spectroscopy and Machine Learning.

Analytical chemistry
Bladder, kidney, and prostate cancers are prevalent urinary cancers, and developing efficient detection methods is of significance for the early diagnosis of them. However, noninvasive and sensitive detection of urinary cancers still challenges tradi...