Whole-cell biosensors (WCBs), which detect targeting analytes through cellular responses, have become powerful tools for environmental monitoring. However, existing WCBs often rely on the single-channel low-dimension signal outputs (e.g., fluorescenc...
Point-of-care (POC) devices have grown in popularity due to their ease of use, low cost, and speedy on-site diagnostic capabilities. This study focuses on ketamine detection by colorimetric and lateral flow assays (LFA), with aptamer-based LFA emergi...
Ferritin is an iron-storage protein that naturally self-assembles into a hollow spherical particle consisting of 24 identical subunits, and it serves a central role in iron metabolism. Ferritin's favorable drug-loading capacity, biocompatibility, int...
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy
Jul 29, 2025
Melamine contamination from illegal additives, packaging contaminants, and pesticide residues threatens dairy product safety, demanding rapid detection. Traditional methods such as chromatography or mass spectrometry are precise but lack field applic...
A non-invasive, enzyme-based colorimetric biosensor was developed for urea detection in saliva, utilizing a growth-based method with Au@Ag core-shell nanostructures, including CTAB-coated gold nanoparticles (AuNPs) and CTAB-coated gold nanorods with ...
Traditional wearable devices for sweat detection often face limitations such as low detection sensitivity, insufficient mechanical properties, and discomfort during use. To address these challenges, hydrogels are utilized as sensor patches to improve...
Surface-enhanced Raman scattering (SERS) has demonstrated remarkable potential for molecular detection due to its specificity. However, detecting fluorescent vitamin B molecules remains challenging due to fluorescence interference and weak Raman cros...
Label-free optical imaging of the morphology of single nanoparticles under native conditions remains a challenging task despite its importance in the synthesis, properties, and applications of nanomaterials. Here, we developed an angular scanning dar...
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy
Jul 2, 2025
Breast cancer remains a global health challenge, with an increasing number of cases necessitating innovative approaches to streamline patient management prior to treatment. In this study, we present a comprehensive aptamer-involved surface-enhanced R...
Early detection of thyroid cancer improves patient survival rate from 51.9% to 99.9%. Fine needle aspiration cytology is the primary method for diagnosing thyroid cancer; however, this method is associated with limitations, including diagnostic uncer...
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