This work reports an efficient method to detect SARS-CoV-2 antibodies in blood samples based on SERS combined with a machine learning tool. For this purpose, gold nanoparticles directly conjugated with spike protein were used in human blood samples t...
Surface enhanced Raman scattering (SERS) has been proved an effective analytical technique due to its high sensitivity, however, how to identify and extract useful information from raw SERS spectra is still a problem that needs to be resolved. In thi...
Advanced materials (Deerfield Beach, Fla.)
39588857
Developing cost-effective, consumer-accessible platforms for point-of-use environmental and clinical pathogen testing is a priority, to reduce reliance on laborious, time-consuming culturing approaches. Unfortunately, a system offering ultrasensitive...
Realizing the intelligent analysis of the intracellular reactive oxygen species (ROS) is beneficial to quick diagnosis of diseases. Herein, surface-enhanced Raman spectroscopy (SERS) technology was combined with deep learning to establish a smart det...
Journal of chemical information and modeling
39546324
Global optimization of the structure of atomic nanoparticles is often hampered by the presence of many funnels on the potential energy surface. While broad funnels are readily encountered and easily exploited by the search, narrow funnels are more di...
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy
39541643
Design of a sensitive, cost-effective SERS substrate is critical for probing analyte in trace concentration in real field environment. Present work reports the fabrication of an oxygen (O) plasma treated bimetallic nanofibers as a sensitive SERS plat...
BACKGROUND: Lanthanide-based nanomaterials offer a promising alternative for cancer therapy because of their selectivity and effectiveness, which can be modified and predicted by leveraging the improved accuracy and enhanced decision-making of machin...
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy
39509865
Metabolites serve as vital biomarkers, reflecting physiological and pathological states and offering insights into disease progression and early detection. This study introduces an advanced analytical technique integrating label-free Surface-Enhanced...
The challenge of rapid identification of bacteria in food and water still persists as a major health problem. To tackle this matter, we have developed a single-probe liquid crystal (LC)-based optical sensing platform for the differentiation of five c...
As nanotechnology advances, metal oxide nanoparticles (MeONPs) increasingly come into contact with humans. The inhaled MeONPs cannot be effectively cleared by cilia or lung mucus. In the last decade, potential immune toxicity arising from exposure to...