AIMC Topic: Mice

Clear Filters Showing 551 to 560 of 1503 articles

DeepDetect: Deep Learning of Peptide Detectability Enhanced by Peptide Digestibility and Its Application to DIA Library Reduction.

Analytical chemistry Mar 12, 2023
In tandem mass spectrometry-based proteomics, proteins are digested into peptides by specific protease(s), but generally only a fraction of peptides can be detected. To characterize detectable proteotypic peptides, we have developed a series of metho...
Mice Peptide Library Proteome Peptides Deep Learning Humans Animals Escherichia coli Proteins Saccharomyces cerevisiae Peptide Hydrolases Tandem Mass Spectrometry
View on PubMed DOI

Improved Repeatability of Mouse Tibia Volume Segmentation in Murine Myelofibrosis Model Using Deep Learning.

Tomography (Ann Arbor, Mich.) Mar 7, 2023
A murine model of myelofibrosis in tibia was used in a co-clinical trial to evaluate segmentation methods for application of image-based biomarkers to assess disease status. The dataset (32 mice with 157 3D MRI scans including 49 test-retest pairs sc...
Humans Image Processing, Computer-Assisted Mice Magnetic Resonance Imaging Animals Tibia Deep Learning Primary Myelofibrosis
View on PubMed DOI

Deep learning enabled multi-organ segmentation of mouse embryos.

Biology open Feb 21, 2023
The International Mouse Phenotyping Consortium (IMPC) has generated a large repository of three-dimensional (3D) imaging data from mouse embryos, providing a rich resource for investigating phenotype/genotype interactions. While the data is freely av...
Polycomb-Group Proteins Embryo, Mammalian Ligases Deep Learning Mice Animals
View on PubMed DOI

Quantifying Inflammatory Response and Drug-Aided Resolution in an Atopic Dermatitis Model with Deep Learning.

The Journal of investigative dermatology Feb 17, 2023
Noninvasive quantification of dermal diseases aids efficacy studies and paves the way for broader enrollment in clinical studies across varied demographics. Related to atopic dermatitis, accurate quantification of the onset and resolution of inflamma...
Dermatitis, Atopic Administration, Topical Inflammation Skin Deep Learning Mice Animals
View on PubMed DOI

Evaluation of mouse behavioral responses to nutritive versus nonnutritive sugar using a deep learning-based 3D real-time pose estimation system.

Journal of neurogenetics Feb 15, 2023
Animals are able to detect the nutritional content of sugar independently of taste. When given a choice between nutritive sugar and nonnutritive sugar, animals develop a preference for nutritive sugar over nonnutritive sugar during a period of food d...
Animals Deep Learning Feeding Behavior Behavior, Animal Mice Sugars
View on PubMed DOI

Image processing and supervised machine learning for retinal microglia characterization in senescence.

Methods in cell biology Jan 28, 2023
The process of senescence impairs the function of cells and can ultimately be a key factor in the development of disease. With an aging population, senescence-related diseases are increasing in prevalence. Therefore, understanding the mechanisms of c...
Microglia Animals Image Processing, Computer-Assisted Supervised Machine Learning Aging Mice Retina
View on PubMed DOI

Quantifying stiffness and forces of tumor colonies and embryos using a magnetic microrobot.

Science robotics Jan 25, 2023
Stiffness and forces are two fundamental quantities essential to living cells and tissues. However, it has been a challenge to quantify both 3D traction forces and stiffness (or modulus) using the same probe in vivo. Here, we describe an approach tha...
Magnetic Phenomena Zebrafish Mice Microgels Animals Robotics Neoplasms
View on PubMed DOI

Brain Data Standards - A method for building data-driven cell-type ontologies.

Scientific data Jan 24, 2023
Large-scale single-cell 'omics profiling is being used to define a complete catalogue of brain cell types, something that traditional methods struggle with due to the diversity and complexity of the brain. But this poses a problem: How do we organise...
Brain Callithrix Animals Data Collection Humans Mice Biological Ontologies
View on PubMed DOI

MultiScale-CNN-4mCPred: a multi-scale CNN and adaptive embedding-based method for mouse genome DNA N4-methylcytosine prediction.

BMC bioinformatics Jan 18, 2023
N4-methylcytosine (4mC) is an important epigenetic mechanism, which regulates many cellular processes such as cell differentiation and gene expression. The knowledge about the 4mC sites is a key foundation to exploring its roles. Due to the limitatio...
Software Animals Epigenesis, Genetic DNA Mice Neural Networks, Computer Genome
View on PubMed DOI

AI-based MRI auto-segmentation of brain tumor in rodents, a multicenter study.

Acta neuropathologica communications Jan 14, 2023
Automatic segmentation of rodent brain tumor on magnetic resonance imaging (MRI) may facilitate biomedical research. The current study aims to prove the feasibility for automatic segmentation by artificial intelligence (AI), and practicability of AI-...
Mice Rats Rodentia Magnetic Resonance Imaging Brain Neoplasms Animals Artificial Intelligence Image Processing, Computer-Assisted
View on PubMed DOI
Popular Topics
Recent Journals