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Molecular Weight

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Effect of sprint training on resting serum irisin concentration - Sprint training once daily vs. twice every other day.

Metabolism: clinical and experimental
OBJECTIVE: Exercise twice every other day has been shown to lead to increasing peroxisome proliferator receptor γ coactivator-1α (PGC-1α) expression (up-stream factor of irisin) via lowered muscle glycogen level during second of exercise compared wit...

Purification and biochemical properties of SDS-stable low molecular weight alkaline serine protease from Citrullus colocynthis.

Natural product research
A low molecular weight serine protease from seeds of Citrullus colocynthis was purified to electrophoretic homogeneity with high level of catalytic efficiency (22,945 M(-1) S(-1)). The enzyme was a monomer with molecular mass of 25 kDa estimated by S...

Development of a Support Vector Machine-Based System to Predict Whether a Compound Is a Substrate of a Given Drug Transporter Using Its Chemical Structure.

Journal of pharmaceutical sciences
The aim of this study was to develop an in silico prediction system to assess which of 7 categories of drug transporters (organic anion transporting polypeptide [OATP] 1B1/1B3, multidrug resistance-associated protein [MRP] 2/3/4, organic anion transp...

Knodle: A Support Vector Machines-Based Automatic Perception of Organic Molecules from 3D Coordinates.

Journal of chemical information and modeling
Here we address the problem of the assignment of atom types and bond orders in low molecular weight compounds. For this purpose, we have developed a prediction model based on nonlinear Support Vector Machines (SVM), implemented in a KNOwledge-Driven ...

Predicting the Presence of Uncommon Elements in Unknown Biomolecules from Isotope Patterns.

Analytical chemistry
The determination of the molecular formula is one of the earliest and most important steps when investigating the chemical nature of an unknown compound. Common approaches use the isotopic pattern of a compound measured using mass spectrometry. Compu...

[Thalamocortical Neural Mass Model Simulation and Study Based on Field Programmable Gate Array].

Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi
Using the computer to imitate the neural oscillations of the brain is of great significance for the analysis of brain functions.Thalamocortical neural mass model(TNMM)reflects the mechanisms of neural activities by establishing the relationships betw...

Advancing the large-scale CCS database for metabolomics and lipidomics at the machine-learning era.

Current opinion in chemical biology
Metabolomics and lipidomics aim to comprehensively measure the dynamic changes of all metabolites and lipids that are present in biological systems. The use of ion mobility-mass spectrometry (IM-MS) for metabolomics and lipidomics has facilitated the...

Effects of corn straw on dissipation of polycyclic aromatic hydrocarbons and potential application of backpropagation artificial neural network prediction model for PAHs bioremediation.

Ecotoxicology and environmental safety
In order to provide a viable option for remediation of PAHs-contaminated soils, a greenhouse experiment was conducted to assess the effect of corn straw amendment (1%, 2%, 4% or 6%, w/w) on dissipation of aged polycyclic aromatic hydrocarbons (PAHs) ...