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Monte Carlo Method

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Improvement of deep learning-based dose conversion accuracy to a Monte Carlo algorithm in proton beam therapy for head and neck cancers.

Journal of radiation research
This study is aimed to clarify the effectiveness of the image-rotation technique and zooming augmentation to improve the accuracy of the deep learning (DL)-based dose conversion from pencil beam (PB) to Monte Carlo (MC) in proton beam therapy (PBT). ...

The Harms of Class Imbalance Corrections for Machine Learning Based Prediction Models: A Simulation Study.

Statistics in medicine
INTRODUCTION: Risk prediction models are increasingly used in healthcare to aid in clinical decision-making. In most clinical contexts, model calibration (i.e., assessing the reliability of risk estimates) is critical. Data available for model develo...

Individualized multi-treatment response curves estimation using RBF-net with shared neurons.

Biometrics
Heterogeneous treatment effect estimation is an important problem in precision medicine. Specific interests lie in identifying the differential effect of different treatments based on some external covariates. We propose a novel non-parametric treatm...

Grand canonical Monte Carlo and deep learning assisted enhanced sampling to characterize the distribution of Mg2+ and influence of the Drude polarizable force field on the stability of folded states of the twister ribozyme.

The Journal of chemical physics
Molecular dynamics simulations are crucial for understanding the structural and dynamical behavior of biomolecular systems, including the impact of their environment. However, there is a gap between the time scale of these simulations and that of rea...

A deep learning feature importance test framework for integrating informative high-dimensional biomarkers to improve disease outcome prediction.

Briefings in bioinformatics
Many human diseases result from a complex interplay of behavioral, clinical, and molecular factors. Integrating low-dimensional behavioral and clinical features with high-dimensional molecular profiles can significantly improve disease outcome predic...

Determination of neutron spectrum based on artificial neural network using liquid scintillation detector EJ-301.

Radiation protection dosimetry
This paper focuses on the neutron spectrum measurement using a liquid scintillation detector, where the neutron spectrum could be identified and unfolded from the light output distribution of the EJ-301 liquid scintillation detector through a linear ...

Rapid assessment of cosmic radiation exposure in aviation based on BP neural network method.

Radiation protection dosimetry
Cosmic radiation exposure is one of the important health concerns for aircrews. In this work, we constructed a back propagation neural network model for the real-time and rapid assessment of cosmic radiation exposure to the public in aviation. The mu...

A Bayesian convolutional neural network-based generalized linear model.

Biometrics
Convolutional neural networks (CNNs) provide flexible function approximations for a wide variety of applications when the input variables are in the form of images or spatial data. Although CNNs often outperform traditional statistical models in pred...

Predicting patient-specific organ doses from thoracic CT examinations using support vector regression algorithm.

Journal of X-ray science and technology
PURPOSE: This study aims to propose and develop a fast, accurate, and robust prediction method of patient-specific organ doses from CT examinations using minimized computational resources.

IsoFrog: a reversible jump Markov Chain Monte Carlo feature selection-based method for predicting isoform functions.

Bioinformatics (Oxford, England)
MOTIVATION: A single gene may yield several isoforms with different functions through alternative splicing. Continuous efforts are devoted to developing machine-learning methods to predict isoform functions. However, existing methods do not consider ...