Neurology(R) neuroimmunology & neuroinflammation
Aug 19, 2025
BACKGROUND AND OBJECTIVES: In multiple sclerosis (MS), neurodegeneration results from the interplay between disease-specific pathology and normal aging. Conventional MRI captures morphologic changes in neurodegeneration, while quantitative MRI (qMRI)...
Multiple sclerosis (MS) is a chronic disease of the central nervous system. The occurrence of MS is a phased process while its cause is still unclear. Here, by combining white matter single-nucleus transcriptomic datasets from MS and control samples,...
BACKGROUND AND OBJECTIVES: Although disease-modifying therapies (DMTs) may suppress coronavirus disease 2019 (COVID-19) vaccine responses in people with multiple sclerosis (pwMS), limited data are available on the cumulative effect of additional boos...
Multiple sclerosis (MS) is a multifaceted, chronic neuroinflammatory condition of the central nervous system (CNS) marked by demyelination, gliosis, and axonal degradation. Despite the comprehensive investigation, the exact etiology remains unclear, ...
Multiple Sclerosis (MS) is a chronic autoimmune disease that primarily affects the central nervous system and is predominantly diagnosed in adults, making pediatric cases rare and underrepresented in medical research. This paper introduces the first ...
Journal of neuroengineering and rehabilitation
Jul 5, 2025
The goal of this work was to develop an adaptive rehabilitation technique using a haptic wrist robot that would induce cross-education to an untrained limb. Fourteen individuals with Multiple Sclerosis (MS) and eight non-affected adults completed an ...
BACKGROUND: The choroid plexus (ChP) plays a pivotal role in inflammatory processes that occur in multiple sclerosis (MS). The enlargement of the ChP in relapsing-remitting multiple sclerosis (RRMS) is considered to be an indication of disease activi...
Multiple Sclerosis (MS) is a chronic neuroinflammatory disease of the Central Nervous System (CNS) in which the body's immune system attacks and destroys the myelin sheath that protects nerve fibers, leading to a wide range of debilitating symptoms a...
Multiple sclerosis and related disorders
Apr 22, 2025
BACKGROUND: The choroid plexus (CP) is closely linked to inflammation in multiple sclerosis (MS). While the CP volume is enlarged in MS compared with healthy controls (HC), no such changes are observed in neuromyelitis optica spectrum disorder (NMOSD...
OBJECTIVE: To develop a deep learning (DL) model for the detection of spinal cord (SC) multiple sclerosis (MS) lesions from both sagittal T2 and short tau inversion recovery (STIR) sequences and to investigate whether such a model could improve the p...
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