AIMC Topic: Mutation

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A neural network prediction of environmental determinants of Anopheles sinensis knockdown resistance mutation to pyrethroids in China.

Journal of vector ecology : journal of the Society for Vector Ecology Dec 1, 2016
Selection pressure caused by long-term intensive use of insecticides is the key driving force in resistance development. Additional parameters such as environmental conditions may affect both the mosquito response to insecticides and the selection of...
Animals China Neural Networks, Computer Environment Insecticide Resistance Anopheles Mutation Pyrethrins
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Optimization of the Production of Extracellular Polysaccharide from the Shiitake Medicinal Mushroom Lentinus edodes (Agaricomycetes) Using Mutation and a Genetic Algorithm-Coupled Artificial Neural Network (GA-ANN).

International journal of medicinal mushrooms Jan 1, 2016
Exopolysaccharide (EPS) production by a strain of Lentinus edodes was studied via the effects of treatments with ultraviolet (UV) irradiation and acridine orange. Furthermore, optimization of EPS production was studied using a genetic algorithm coupl...
Biphenyl Compounds Shiitake Mushrooms Neural Networks, Computer Picrates Mutation Free Radical Scavengers Gene Expression Regulation, Fungal Fungal Polysaccharides
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Long-term Virologic Suppression Despite Presence of Resistance-associated Mutations Among Perinatally HIV-infected Youth.

The Pediatric infectious disease journal Dec 1, 2015
BACKGROUND: There is limited information on long-term consequences of continuing combination antiretroviral therapy (cART) consisting of <3 active drugs in treatment-experienced youth with perinatal HIV (PHIV). This study describes the clinical outco...
Mutation Anti-Retroviral Agents Adult Viral Load Humans Infectious Disease Transmission, Vertical Female HIV-1 CD4 Lymphocyte Count Retrospective Studies Male Adolescent Drug Resistance, Viral Young Adult HIV Infections
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Mutation analysis of 6 spinocerebellar ataxia (SCA) types in patients from southern Turkey.

Turkish journal of medical sciences Jan 1, 2015
BACKGROUND/AIM: Spinocerebellar ataxias (SCAs) are complex clinical and genetically heterogeneous, mostly autosomal dominant neurodegenerative diseases. At present, more than 30 hereditary SCA types have been associated with different gene mutations....
Child, Preschool Child Turkey Calcium Channels Mutation Case-Control Studies Adolescent Adult Trinucleotide Repeats Humans Middle Aged Young Adult TATA-Box Binding Protein Consanguinity Ataxins Spinocerebellar Ataxias
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Machine learning from concept to clinic: reliable detection of BRAF V600E DNA mutations in thyroid nodules using high-dimensional RNA expression data.

Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing Jan 1, 2015
The promise of personalized medicine will require rigorously validated molecular diagnostics developed on minimally invasive, clinically relevant samples. Measurement of DNA mutations is increasingly common in clinical settings but only higher-preval...
RNA, Neoplasm DNA Mutational Analysis Biopsy, Fine-Needle Oligonucleotide Array Sequence Analysis Proto-Oncogene Proteins B-raf DNA, Neoplasm Mutation High-Throughput Nucleotide Sequencing Computational Biology Support Vector Machine Humans Gene Expression Profiling Thyroid Nodule Machine Learning
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Epistasis analysis using artificial intelligence.

Methods in molecular biology (Clifton, N.J.) Jan 1, 2015
Here we introduce artificial intelligence (AI) methodology for detecting and characterizing epistasis in genetic association studies. The ultimate goal of our AI strategy is to analyze genome-wide genetics data as a human would using sources of exper...
Glaucoma Artificial Intelligence Humans Models, Genetic Prostatic Neoplasms Mutation Software Male Alzheimer Disease Epistasis, Genetic
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