AIMC Topic: Nephrotic Syndrome

Clear Filters Showing 1 to 4 of 4 articles

Applying exposure-response analysis to enhance Mycophenolate Mofetil dosing precision in pediatric patients with immune-mediated renal diseases by machine learning models.

European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences May 28, 2025
BACKGROUND: Mycophenolate mofetil (MMF), a cornerstone immunosuppressant for lupus nephritis, is increasingly used off-label in pediatric immune-mediated renal diseases. The aims of this study were to develop and validate pharmacokinetic models for m...
Humans Machine Learning Female Male Adolescent Child, Preschool Child Dose-Response Relationship, Drug Immunosuppressive Agents Kidney Diseases Models, Biological Mycophenolic Acid Nephrotic Syndrome
View on PubMed DOI

Artificial intelligence-based personalised rituximab treatment protocol in membranous nephropathy (iRITUX): protocol for a multicentre randomised control trial.

BMJ open Apr 2, 2025
INTRODUCTION: Membranous nephropathy is an autoimmune kidney disease and the most common cause of nephrotic syndrome in non-diabetic Caucasian adults. Rituximab is now recommended as first-line therapy for membranous nephropathy. However, Kidney Dise...
Humans Artificial Intelligence Algorithms Prospective Studies Precision Medicine Female Adult Male Multicenter Studies as Topic Randomized Controlled Trials as Topic Immunologic Factors Glomerulonephritis, Membranous France Rituximab Nephrotic Syndrome
View on PubMed DOI

Deep learning analysis of clinical course of primary nephrotic syndrome: Japan Nephrotic Syndrome Cohort Study (JNSCS).

Clinical and experimental nephrology Aug 12, 2022
BACKGROUND: Prognosis of nephrotic syndrome has been evaluated based on pathological diagnosis, whereas its clinical course is monitored using objective items and the treatment strategy is largely the same. We examined whether the entire natural hist...
Humans Deep Learning Cohort Studies Creatinine Japan Proteinuria Hematuria Nephrotic Syndrome
View on PubMed DOI

Biopsy-Free Prediction of Pathologic Type of Primary Nephrotic Syndrome Using a Machine Learning Algorithm.

Kidney & blood pressure research Dec 4, 2017
BACKGROUND/AIMS: Renal biopsy is the gold standard to determine the pathologic type of primary nephrotic syndrome, which is critical for diagnosis, choice of treatment and evaluation of prognosis. However, in some cases, renal biopsy cannot be perfor...
Humans Machine Learning Algorithms Prognosis Female Adult Male Predictive Value of Tests Biopsy Nephrotic Syndrome
View on PubMed DOI
Popular Topics
Recent Journals