AIMC Topic: Nervous System Diseases

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Neur-Ally: a deep learning model for regulatory variant prediction based on genomic and epigenomic features in brain and its validation in certain neurological disorders.

NAR genomics and bioinformatics
Large-scale quantitative studies have identified significant genetic associations for various neurological disorders. Expression quantitative trait locusĀ (eQTL) studies have shown the effect of single-nucleotide polymorphisms (SNPs) on the differenti...

Automated inference of disease mechanisms in patient-hiPSC-derived neuronal networks.

Communications biology
Human induced pluripotent stem cells (hiPSCs)-derived neuronal networks on multi-electrode arrays (MEAs) are a powerful tool for studying neurological disorders. The electric activity patterns of these networks differ between healthy and patient-deri...

Validation of an Artificial Intelligence-Powered Virtual Assistant for Emergency Triage in Neurology.

The neurologist
OBJECTIVES: Neurological emergencies pose significant challenges in medical care in resource-limited countries. Artificial intelligence (AI), particularly health chatbots, offers a promising solution. Rigorous validation is required to ensure safety ...

Significance of NMDA receptor-targeting compounds in neuropsychological disorders: An in-depth review.

European journal of pharmacology
N-methyl-D-aspartate receptors (NMDARs), a subclass of glutamate-gated ion channels, play an integral role in the maintenance of synaptic plasticity and excitation-inhibition balance within the central nervous system (CNS). Any irregularities in NMDA...

Documentation, Coding, and Billing for Neurologic Services and Procedures.

Seminars in neurology
Documentation, coding, and billing (claims submission) are foundational to neurologic practice in the United States, enabling accurate reimbursement, effective communication, and data-driven advancements in patient care, research, and education. Neur...

Computational modelling for risk assessment of neurological disorder in diabetes using Hodgkin-Huxley model.

Computer methods and programs in biomedicine
BACKGROUND: Diabetes mellitus, characterized by chronic glucose dysregulation, significantly increases the risk of neurological disorders such as cognitive decline, seizures, and Alzheimer's disease. As neurons depend on glucose for energy, fluctuati...

An enhanced CNN-Bi-transformer based framework for detection of neurological illnesses through neurocardiac data fusion.

Scientific reports
Classical approaches to diagnosis frequently rely on self-reported symptoms or clinician observations, which can make it difficult to examine mental health illnesses due to their subjective and complicated nature. In this work, we offer an innovative...

Non-Face-to-Face Services in Neurologic Care.

Seminars in neurology
Neurologists in ambulatory settings struggle with low appointment availability and increased work related to patient care outside of clinic visits. Neurologists can better meet these demands using asynchronous or non-face-to-face care options. Specif...

Strategies for mitigating data heterogeneities in AI-based neuro-disease detection.

Neuron
In this NeuroView, we discuss challenges and best practices when dealing with disease-detection AI models that are trained on heterogeneous clinical data, focusing on the interrelated problems of model bias, causality, and rare diseases.

Electroencephalogram (EEG) Based Fuzzy Logic and Spiking Neural Networks (FLSNN) for Advanced Multiple Neurological Disorder Diagnosis.

Brain topography
Neurological disorders are a major global health concern that have a substantial impact on death rates and quality of life. accurately identifying a number of diseases Due to inherent data uncertainties and Electroencephalogram (EEG) pattern overlap,...