AIMC Topic: Neural Networks, Computer

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A deep learning model for prediction of lysine crotonylation sites by fusing multi-features based on multi-head self-attention mechanism.

Scientific reports
Lysine crotonylation (Kcr) is an important post-translational modification, which is present in both histone and non-histone proteins, and plays a key role in a variety of biological processes such as metabolism and cell differentiation. Therefore, r...

scMODAL: a general deep learning framework for comprehensive single-cell multi-omics data alignment with feature links.

Nature communications
Recent advancements in single-cell technologies have enabled comprehensive characterization of cellular states through transcriptomic, epigenomic, and proteomic profiling at single-cell resolution. These technologies have significantly deepened our u...

Machine Learning and Deep Learning Techniques for Prediction and Diagnosis of Leptospirosis: Systematic Literature Review.

JMIR medical informatics
BACKGROUND: Leptospirosis, a zoonotic disease caused by Leptospira bacteria, continues to pose significant public health risks, particularly in tropical and subtropical regions.

NeuroScale: evolutional scale-based protein language models enable prediction of neuropeptides.

BMC biology
BACKGROUND: Neuropeptides (NPs) are critical signaling molecules involved in various physiological and behavioral processes, including development, metabolism, and memory. They function within both the nervous and endocrine systems and have emerged a...

A novel approach for multiclass sentiment analysis on Chinese social media with ERNIE-MCBMA.

Scientific reports
Weibo, one of the most widely used social media platforms in China, sees a vast number of users expressing their opinions and emotional tendencies. Conducting sentiment analysis on Weibo posts using natural language processing techniques is crucial f...

LGLoc as a new language model-driven graph neural network for mRNA localization.

Scientific reports
The localization of mRNA is crucial for the synthesis of functional proteins and plays a significant role in cellular processes. Understanding mRNA localization can enhance applications in disease diagnosis (e.g., cancer, Alzheimer's) and drug develo...

GraftIQ: Hybrid multi-class neural network integrating clinical insight for multi-outcome prediction in liver transplant recipients.

Nature communications
Liver transplant recipients (LTRs) are at risk of graft injury, leading to cirrhosis and reduced survival. Liver biopsy, the diagnostic gold standard, is invasive and risky. We developed a hybrid multi-class neural network (NN) model, 'GraftIQ,' inte...

Artificial Axon with Dendritic-like Plasticity by Biomimetic Interface Engineering of Anisotropic Two-Dimensional Tellurium.

Nano letters
Spiking neural network (SNN) hardware relies on implicit assumptions that prioritize dendritic/synaptic learning above axon/synaptic concerns, compromising performances in signal capacity, accuracy, and compactness of SNN systems. Herein, we develop ...

Automatic assessment of lower limb deformities using high-resolution X-ray images.

BMC musculoskeletal disorders
BACKGROUND: Planning an osteotomy or arthroplasty surgery on a lower limb requires prior classification/identification of its deformities. The detection of skeletal landmarks and the calculation of angles required to identify the deformities are trad...