Alzheimer's & dementia : the journal of the Alzheimer's Association
Aug 1, 2025
INTRODUCTION: Clinical diagnosis (normal cognition, mild cognitive impairment [MCI], dementia) is critical for understanding cognitive impairment and dementia but can be resource intensive and subject to inconsistencies due to complex clinical judgme...
BACKGROUND AND OBJECTIVES: Cerebrovascular disease (CeVD) and cognitive impairment risk factors contribute to cognitive decline, but the role of brain age gap (BAG) in mediating this relationship remains unclear, especially in Southeast Asian populat...
As the older adult population continues to expand, the demands on the healthcare system intensifies, necessitating the development of technologies that effectively accommodate the requirements of older adults. While Artificial Intelligence (AI) syste...
The journals of gerontology. Series B, Psychological sciences and social sciences
Jun 10, 2025
OBJECTIVES: Device-based sedentary time shows a nonlinear association with incident dementia among older adults. However, associations between sedentary time and cognitive performance have been inconsistent. We examined potential nonlinear associatio...
BACKGROUND: Cognitive impairment is common but frequently undiagnosed in the dialysis population. We aimed to develop and validate a quick and accurate screening tool using machine-learning-based approaches in them.
There is an urgent need for the precise prediction of cerebral amyloidosis using noninvasive and accessible indicators to facilitate the early diagnosis of individuals with the preclinical stage of Alzheimer's disease (AD). Two hundred and four indiv...
BACKGROUND AND OBJECTIVES: Cortical lesions in multiple sclerosis (MS) severely affect cognition, but their longitudinal evolution and impact on specific cognitive functions remain understudied. This study investigates the evolution of function-speci...
Structural neuroimaging studies of patients with Juvenile Myoclonic Epilepsy (JME) typically present two findings: 1-volume reduction of subcortical gray matter structures, and 2-abnormalities of cortical thickness. The general trend has been to obse...
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry
May 1, 2025
BACKGROUND: Primary healthcare institutions find identifying individuals with dementia particularly challenging. This study aimed to develop machine learning models for identifying predictive features of older adults with normal cognition to develop ...
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