AIMC Topic: Observational Studies as Topic

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Long-term mesh erosion rate following abdominal robotic reconstructive pelvic floor surgery: a prospective study and overview of the literature.

International urogynecology journal
INTRODUCTION AND HYPOTHESIS: The use of synthetic mesh in transvaginal pelvic floor surgery has been subject to debate internationally. Although mesh erosion appears to be less associated with an abdominal approach, the long-term outcome has not been...

Machine learning methods for developing precision treatment rules with observational data.

Behaviour research and therapy
Clinical trials have identified a variety of predictor variables for use in precision treatment protocols, ranging from clinical biomarkers and symptom profiles to self-report measures of various sorts. Although such variables are informative collect...

A comparison of machine learning algorithms and covariate balance measures for propensity score matching and weighting.

Biometrical journal. Biometrische Zeitschrift
Propensity score matching (PSM) and propensity score weighting (PSW) are popular tools to estimate causal effects in observational studies. We address two open issues: how to estimate propensity scores and assess covariate balance. Using simulations,...

Estimating the Population Average Treatment Effect in Observational Studies with Choice-Based Sampling.

The international journal of biostatistics
We consider causal inference in observational studies with choice-based sampling, in which subject enrollment is stratified on treatment choice. Choice-based sampling has been considered mainly in the econometrics literature, but it can be useful for...

Machine learning in whole-body MRI: experiences and challenges from an applied study using multicentre data.

Clinical radiology
Machine learning is now being increasingly employed in radiology to assist with tasks such as automatic lesion detection, segmentation, and characterisation. We are currently involved in an National Institute of Health Research (NIHR)-funded project,...

Using classification tree analysis to generate propensity score weights.

Journal of evaluation in clinical practice
RATIONALE, AIMS AND OBJECTIVES: In evaluating non-randomized interventions, propensity scores (PS) estimate the probability of assignment to the treatment group given observed characteristics. Machine learning algorithms have been proposed as an alte...

Targeted Maximum Likelihood Estimation for Causal Inference in Observational Studies.

American journal of epidemiology
Estimation of causal effects using observational data continues to grow in popularity in the epidemiologic literature. While many applications of causal effect estimation use propensity score methods or G-computation, targeted maximum likelihood esti...

Using machine learning to assess covariate balance in matching studies.

Journal of evaluation in clinical practice
In order to assess the effectiveness of matching approaches in observational studies, investigators typically present summary statistics for each observed pre-intervention covariate, with the objective of showing that matching reduces the difference ...

Vitamin D status in relation to Crohn's disease: Meta-analysis of observational studies.

Nutrition (Burbank, Los Angeles County, Calif.)
OBJECTIVES: Inconsistent findings have been published regarding vitamin D status among patients with Crohn's disease (CD) and the association with disease severity. We aimed to perform a meta-analysis evaluating serum 25-hydroxy vitamin D and 1,25 de...

External Validation of an Algorithm to Guide Opioid Administration at the End of Surgery-Protocol for an Observational Cohort Study of the OPIAID Algorithm.

Acta anaesthesiologica Scandinavica
BACKGROUND: Despite advances in pain management, inadequate pain relief and opioid-related adverse events remain common challenges in perioperative care, often contributing to prolonged recovery and reduced quality of life. The perioperative opioid a...