AIMC Topic: Parathyroid Hormone
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Using machine learning models for predicting monthly iPTH levels in hemodialysis patients.
Computer methods and programs in biomedicine
Nov 30, 2024
BACKGROUND AND OBJECTIVE: Intact parathyroid hormone (iPTH), also known as active parathyroid hormone, is an important indicator commonly for monitoring secondary hyperparathyroidism (SHPT) in patients undergoing hemodialysis. The aim of this study w...
Study on the Effect of Low Calcium Dialysate on Biochemical Profile of Adynamic Bone Disease in Patients on Maintenance Hemodialysis.
Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia
Jan 17, 2024
In recent years, adynamic bone disease (ABD) has become a common skeletal lesion in adult patients with chronic kidney disease. We aimed to compare the effects of low calcium dialysate (LCD) and standard calcium dialysate of our facility [high calciu...
De novo design of high-affinity binders of bioactive helical peptides.
Nature
Dec 18, 2023
Many peptide hormones form an α-helix on binding their receptors, and sensitive methods for their detection could contribute to better clinical management of disease. De novo protein design can now generate binders with high affinity and specificity ...
Robot-Assisted Parathyroidectomy Using Indocyanine Green (ICG) Fluorescence in Primary Hyperparathyroidism.
Medicina (Kaunas, Lithuania)
Aug 12, 2023
: Surgical treatment for primary hyperparathyroidism (PHPT) has evolved from bilateral exploration through a long transcervical incision to focused parathyroidectomy with a minimal incision above the pathologic gland. Recently, endoscopic or robot-as...
Development of a quantitative systems pharmacology model of chronic kidney disease: metabolic bone disorder.
American journal of physiology. Renal physiology
Dec 14, 2020
Chronic kidney disease mineral bone disorder (CKD-MBD) is a virtually universal complication of kidney diseases, starting early in the course of disease and resulting in devastating clinical consequences ranging from bone fragility to accelerated ath...
[Seasonal variations in 25-hydroxy vitamin D3, parathormone and alkaline phosphatase in school-aged children].
Revista chilena de pediatria
Nov 5, 2020
INTRODUCTION: The main role of Vitamin D is to regulate calcium metabolism, whose main source is vitamin D3 ob tained mostly from the action of ultraviolet (UV) light on the skin.
[Long-term efficacy of parathyroidectomy in secondary and tertiary hyperparathyroidism].
Revista medica del Instituto Mexicano del Seguro Social
Dec 30, 2019
BACKGROUND: Secondary and tertiary hyperparathyroidism (SHPT and THPT), are complications of chronic kidney disease (CKD), characterized by high levels of serum parathormone, hyperphosphatemia or hypercalcemia, respectively. If diet and pharmacologic...
Factors involved in phenoconversion of CYP3A using 4β-hydroxycholesterol in stable kidney transplant recipients.
Pharmacological reports : PR
Dec 15, 2018
BACKGROUND: Phenoconversion is a phenomenon whereby some genotypic extensive metabolizers transiently exhibit drug metabolizing enzyme activity at similar level as that of poor metabolizers. Renal failure is known to decrease CYP3A activity in humans...
Influence of Pre-renal Transplant Secondary Hyperparathyroidism on Later Evolution After Transplantation.
Transplantation proceedings
Dec 12, 2018
Persistence of secondary hyperparathyroidism (SHPT) is common after renal transplantation. Good diagnosis and treatment are important to avoid complications. The objective of our work was to perform a retrospective analysis of the evolution of SHPT a...
Non-surgical management of primary hyperparathyroidism.
Best practice & research. Clinical endocrinology & metabolism
Sep 28, 2018
The purpose of this chapter is to discuss the options available for patients with primary hyperparathyrodism (PHPT) not undergoing parathyroidectomy (PTx). Adequate hydration should be recommended in all patients. Calcium intake should not be restric...
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