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Parathyroid Hormone

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Study on the Effect of Low Calcium Dialysate on Biochemical Profile of Adynamic Bone Disease in Patients on Maintenance Hemodialysis.

Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia
In recent years, adynamic bone disease (ABD) has become a common skeletal lesion in adult patients with chronic kidney disease. We aimed to compare the effects of low calcium dialysate (LCD) and standard calcium dialysate of our facility [high calciu...

Surgical management of secondary hyperparathyroidism in dialysis patients in Senegal.

Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia
Secondary hyperparathyroidism (SHPT) is a common complication of end-stage renal disease. Surgical management occurs in severe forms and/or unresponsive medical treatment. The aim of this study was to outline the indications of parathyroidectomy and ...

[Seasonal variations in 25-hydroxy vitamin D3, parathormone and alkaline phosphatase in school-aged children].

Revista chilena de pediatria
INTRODUCTION: The main role of Vitamin D is to regulate calcium metabolism, whose main source is vitamin D3 ob tained mostly from the action of ultraviolet (UV) light on the skin.

[Long-term efficacy of parathyroidectomy in secondary and tertiary hyperparathyroidism].

Revista medica del Instituto Mexicano del Seguro Social
BACKGROUND: Secondary and tertiary hyperparathyroidism (SHPT and THPT), are complications of chronic kidney disease (CKD), characterized by high levels of serum parathormone, hyperphosphatemia or hypercalcemia, respectively. If diet and pharmacologic...

Influence of Pre-renal Transplant Secondary Hyperparathyroidism on Later Evolution After Transplantation.

Transplantation proceedings
Persistence of secondary hyperparathyroidism (SHPT) is common after renal transplantation. Good diagnosis and treatment are important to avoid complications. The objective of our work was to perform a retrospective analysis of the evolution of SHPT a...

Development of a quantitative systems pharmacology model of chronic kidney disease: metabolic bone disorder.

American journal of physiology. Renal physiology
Chronic kidney disease mineral bone disorder (CKD-MBD) is a virtually universal complication of kidney diseases, starting early in the course of disease and resulting in devastating clinical consequences ranging from bone fragility to accelerated ath...

Prediction of all-cause mortality for chronic kidney disease patients using four models of machine learning.

Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association
BACKGROUND: The prediction tools developed from general population data to predict all-cause mortality are not adapted to chronic kidney disease (CKD) patients, because this population displays a higher mortality risk. This study aimed to create a cl...

Robot-Assisted Parathyroidectomy Using Indocyanine Green (ICG) Fluorescence in Primary Hyperparathyroidism.

Medicina (Kaunas, Lithuania)
: Surgical treatment for primary hyperparathyroidism (PHPT) has evolved from bilateral exploration through a long transcervical incision to focused parathyroidectomy with a minimal incision above the pathologic gland. Recently, endoscopic or robot-as...

De novo design of high-affinity binders of bioactive helical peptides.

Nature
Many peptide hormones form an α-helix on binding their receptors, and sensitive methods for their detection could contribute to better clinical management of disease. De novo protein design can now generate binders with high affinity and specificity ...

Using machine learning models for predicting monthly iPTH levels in hemodialysis patients.

Computer methods and programs in biomedicine
BACKGROUND AND OBJECTIVE: Intact parathyroid hormone (iPTH), also known as active parathyroid hormone, is an important indicator commonly for monitoring secondary hyperparathyroidism (SHPT) in patients undergoing hemodialysis. The aim of this study w...