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Parkinson Disease

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Differential diagnosis of multiple system atrophy with predominant parkinsonism and Parkinson's disease using neural networks (part II).

Journal of the neurological sciences
Neural networks (NNs) possess the capability to learn complex data relationships, recognize inherent patterns by emulating human brain functions, and generate predictions based on novel data. We conducted deep learning utilizing an NN to differentiat...

Significance of gender, brain region and EEG band complexity analysis for Parkinson's disease classification using recurrence plots and machine learning algorithms.

Physical and engineering sciences in medicine
Parkinson Disease (PD) is a complex neurological disorder attributed by loss of neurons generating dopamine in the SN per compacta. Electroencephalogram (EEG) plays an important role in diagnosing PD as it offers a non-invasive continuous assessment ...

Efficient recognition of Parkinson's disease mice on stepping characters with CNN.

Scientific reports
Parkinson's disease (PD), as the second most prevalent neurodegenerative disorder worldwide, impacts the quality of life for over 12 million patients. This study aims to enhance the accuracy of early diagnosis of PD through non-invasive methods, with...

PIDGN: An explainable multimodal deep learning framework for early prediction of Parkinson's disease.

Journal of neuroscience methods
BACKGROUND: Parkinson's disease (PD), the second most common neurodegenerative disease in the world, is usually not diagnosed until the later stages of the disease, when patients might have already missed the best treatment period. Therefore, more ef...

Automated analysis of spoken language differentiates multiple system atrophy from Parkinson's disease.

Journal of neurology
BACKGROUND AND OBJECTIVES: Patients with synucleinopathies such as multiple system atrophy (MSA) and Parkinson's disease (PD) frequently display speech and language abnormalities. We explore the diagnostic potential of automated linguistic analysis o...

Efficient Neural Network Classification of Parkinson's Disease and Schizophrenia Using Resting-State EEG Data.

Brain topography
Timely identification of Parkinson's disease and schizophrenia is crucial for the effective management and enhancement of patients' quality of life. The utilization of electroencephalogram (EEG) monitoring applications has proven instrumental in diag...

Analysis of Two Neuroanatomical Subtypes of Parkinson's Disease and Their Motor Progression Based on Semi-Supervised Machine Learning.

CNS neuroscience & therapeutics
BACKGROUND: The high heterogeneity of Parkinson's disease (PD) hinders personalized interventions. Brain structure reflects damage and neuroplasticity and is one of the biological bases of symptomatology. Subtyping PD in the framework of brain struct...

Review on computational methods for the detection and classification of Parkinson's Disease.

Computers in biology and medicine
BACKGROUND AND OBJECTIVE: The worldwide estimates reveal two-fold increase in incidence of Parkinson's disease (PD) over 25 years. The two-fold increased incidence and lack of proper treatment uplifted a compelling solicitude, nagging towards accurat...

Machine Learning-based World Health Organization Disability Assessment Schedule for persons with Parkinson's disease.

Parkinsonism & related disorders
INTRODUCTION: The World Health Organization Disability Assessment Schedule 2.0 (WHODAS 2.0) is a well-known measure to assess disability in persons with Parkinson's disease (PD). The purpose of this study was to develop a short form of the WHODAS 2.0...

Identification of Depression Subtypes in Parkinson's Disease Patients via Structural MRI Whole-Brain Radiomics: An Unsupervised Machine Learning Study.

CNS neuroscience & therapeutics
OBJECTIVE: Current clinical evaluation may tend to lack precision in detecting depression in Parkinson's disease (DPD). Radiomics features have gradually shown potential as auxiliary diagnostic tools in identifying and distinguishing different subtyp...