AIMC Topic: Particle Size

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Application of one-class classification using deep learning technique improves the classification of subvisible particles.

Journal of pharmaceutical sciences
Capturing subvisible particles using flow imaging microscopy is useful for evaluating protein aggregates that may induce immunogenicity. Automated labeling is desirable to distinguish harmless components such as silicone oil (SO) from subvisible part...

Improving PM and PM predictions in China from WRF_Chem through a deep learning method: Multiscale depth-separable UNet.

Environmental pollution (Barking, Essex : 1987)
Accurate predictions of atmospheric particulate matter can be applied in providing services for air pollution prevention and control. However, the forecasting accuracy of traditional air quality models is limited owing to model uncertainties. In this...

Machine learning strengthened formulation design of pharmaceutical suspensions.

International journal of pharmaceutics
Many different formulation strategies have been investigated to oppose suboptimal treatment of long-term or chronic conditions, one of which are the nano- and microsuspensions prepared as long-acting injectables to prolong the release of an active ph...

High-throughput point-of-care serum iron testing utilizing machine learning-assisted deep eutectic solvent fluorescence detection platform.

Journal of colloid and interface science
In this study, a high-throughput point-of-care testing (HT-POCT) system for detecting serum iron was developed using a hydrophobic deep eutectic solvent (HDES) fluorescence detection platform. This machine learning-assisted portable platform enables ...

In silico formulation optimization and particle engineering of pharmaceutical products using a generative artificial intelligence structure synthesis method.

Nature communications
Pharmaceutical drug dosage forms are critical for ensuring the effective and safe delivery of active pharmaceutical ingredients to patients. However, traditional formulation development often relies on extensive lab and animal experimentation, which ...

Quantification of Size-Binned Particulate Matter in Electronic Cigarette Aerosols Using Multi-Spectral Optical Sensing and Machine Learning.

Sensors (Basel, Switzerland)
To monitor health risks associated with vaping, we introduce a multi-spectral optical sensor powered by machine learning for real-time characterization of electronic cigarette aerosols. The sensor can accurately measure the mass of particulate matter...

Optimising the production of PLGA nanoparticles by combining design of experiment and machine learning.

International journal of pharmaceutics
Poly(lactic-co-glycolic acid) (PLGA) is a widely used biodegradable polymer in drug delivery and nanoparticle (NP) formulation due to its controlled drug release properties and safety profiles. Among the methods available for NP production, nanopreci...

A Machine Learning-Optimized System for Pulsatile, Photo- and Chemotherapeutic Treatment Using Near-Infrared Responsive MoS-Based Microparticles in a Breast Cancer Model.

ACS nano
Multimodal cancer therapies are often required for progressive cancers due to the high persistence and mortality of the disease and the negative systemic side effects of traditional therapeutic methods. Thus, the development of less invasive modaliti...

Calibration of discrete meta-parameters of bamboo flour based on magnitude analysis and BP neural network.

PloS one
In the research and development of technology and equipment for bamboo products deep processing, such as filling, drying, and medicinal use of bamboo flour (BF), the poor compaction and fluidity of BF materials entails the need for accurate discrete ...

Rheological modelling of apple puree based on machine learning combined Monte Carlo simulation: Insight into the fundamental light- particle structure interaction processes.

Food chemistry
In this work, apple purees from different particle concentration and verifying in size were reconstituted to investigate their impacts on rheological behaviors, optical properties and light interaction at 900-1650 nm. The optical scattering of differ...