IEEE journal of biomedical and health informatics
Feb 6, 2015
The hypertriglyceridemic waist (HW) phenotype is strongly associated with type 2 diabetes; however, to date, no study has assessed the predictive power of phenotypes based on individual anthropometric measurements and triglyceride (TG) levels. The ai...
BACKGROUND: Many ontologies have been developed in biology and these ontologies increasingly contain large volumes of formalized knowledge commonly expressed in the Web Ontology Language (OWL). Computational access to the knowledge contained within t...
OBJECTIVE: The study was designed to validate use of electronic health records (EHRs) for diagnosing bipolar disorder and classifying control subjects.
Understanding the processes of mitochondrial dynamics (fission, fusion, biogenesis, and mitophagy) has been hampered by the lack of automated, deterministic methods to measure mitochondrial morphology from microscopic images. A method to quantify mit...
Biological outcomes are governed by multiple genetic and environmental factors that act in concert. Determining multifactor interactions is the primary topic of interest in recent genetics studies but presents enormous statistical and mathematical ch...
In this review we summarise our recent efforts in trying to understand the role of heterogeneity in cancer progression by using neural networks to characterise different aspects of the mapping from a cancer cells genotype and environment to its pheno...
Pork is the most widely consumed meat globally, and the industry has achieved substantial genetic advancements for several traits using genomic selection. However, traditional linear genomic prediction models may be inadequate for predicting complex ...
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Nov 30, 2025
Machine learning was employed to annotate images of the thoracic aorta, resulting in the identification of additional thoracic-related targets. However, genetic evaluation of the associations among thoracic aortic traits and their shared genes is lac...
BACKGROUND: Autosomal dominant (AD) inheritance often arises through haploinsufficiency, dominant-negative or gain of function (GoF) effects, while autosomal recessive (AR) inheritance generally results from partial or complete loss of function (LoF)...
Breeding for low deoxynivalenol (DON) mycotoxin content in wheat is challenging due to the complexity of the trait and phenotyping limitations. Since phenomic prediction relies on nonadditive effects and genomic prediction on additive effects, their ...
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