AIMC Topic: Precision Medicine

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Improving personalized healthcare with automated longitudinal EHR analysis.

International journal of medical informatics
BACKGROUND: Traditional Electronic Health Record (EHR) data analysis at King's College Hospital relies on extensive manual effort, from data extraction to reporting, limiting efficiency and scalability. This study presents an automated framework for ...

Harnessing the machine learning and nomogram models: elevating prognostication in nonmetastatic gastric cancer with "double invasion" for personalized patient care.

European journal of medical research
OBJECTIVE: To develop and validate a machine learning framework combined with a nomogram for predicting recurrence after radical gastrectomy in patients with vascular and neural invasion.

Artificial Intelligence in cancer epigenomics: a review on advances in pan-cancer detection and precision medicine.

Epigenetics & chromatin
DNA methylation is a fundamental epigenetic modification that regulates gene expression and maintains genomic stability. Consequently, DNA methylation remains a key biomarker in cancer research, playing a vital role in diagnosis, prognosis, and tailo...

Systematic Review: Use of Artificial Intelligence and Unmet Needs in Eosinophilic Oesophagitis.

Alimentary pharmacology & therapeutics
BACKGROUND: Artificial intelligence (AI) has been applied extensively to eosinophilic oesophagitis (EoE), but its clinical impact and comprehensiveness remain unclear.

Practical AI application in psychiatry: historical review and future directions.

Molecular psychiatry
The integration of artificial intelligence (AI) in mental healthcare holds promise for enhancing diagnostic precision, treatment efficacy, and personalized care. Despite AI's potential to analyze vast datasets and identify subtle patterns, its clinic...

AI-Driven Biomarker Discovery and Personalized Allergy Treatment: Utilizing Machine Learning and NGS.

Current allergy and asthma reports
PURPOSEĀ OF REVIEW: This review explores the transformative potential of artificial intelligence (AI) and next-generation sequencing (NGS) in allergy diagnostics and treatment. It focuses on leveraging these technologies to enhance precision in biomar...

DeepSurv-based deep learning model for survival prediction and personalized treatment recommendation in tongue squamous cell carcinoma.

Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery
We developed a DeepSurv-based deep neural network for survival prediction and treatment recommendation in tongue squamous cell carcinoma (TSCC). The model was trained on 2,015 patients from the Surveillance, Epidemiology, and End Results (SEER) datab...

GatorCLR: Personalized predictions of patient outcomes on electronic health records using self-supervised contrastive graph representation.

Journal of biomedical informatics
OBJECTIVE: Recently, there has been growing interest in analyzing large amounts of Electronic Health Record (EHR) data. Patient outcome prediction is a major area of interest in EHR analysis that focuses on predicting the future health status of pati...