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Precursor Cell Lymphoblastic Leukemia-Lymphoma

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An attention-based deep learning for acute lymphoblastic leukemia classification.

Scientific reports
The bone marrow overproduces immature cells in the malignancy known as Acute Lymphoblastic Leukemia (ALL). In the United States, about 6500 occurrences of ALL are diagnosed each year in both children and adults, comprising nearly 25% of pediatric can...

Utilizing Deep Feature Fusion for Automatic Leukemia Classification: An Internet of Medical Things-Enabled Deep Learning Framework.

Sensors (Basel, Switzerland)
Acute lymphoblastic leukemia, commonly referred to as ALL, is a type of cancer that can affect both the blood and the bone marrow. The process of diagnosis is a difficult one since it often calls for specialist testing, such as blood tests, bone marr...

Artificial intelligence reveals the predictions of hematological indexes in children with acute leukemia.

BMC cancer
Childhood leukemia is a prevalent form of pediatric cancer, with acute lymphoblastic leukemia (ALL) and acute myeloid leukemia (AML) being the primary manifestations. Timely treatment has significantly enhanced survival rates for children with acute ...

Machine learning-based evaluation of prognostic factors for mortality and relapse in patients with acute lymphoblastic leukemia: a comparative simulation study.

BMC medical informatics and decision making
BACKGROUND: Predicting mortality and relapse in children with acute lymphoblastic leukemia (ALL) is crucial for effective treatment and follow-up management. ALL is a common and deadly childhood cancer that often relapses after remission. In this stu...

Differential impact of CD34+ cell dose for different age groups in allogeneic hematopoietic cell transplantation for acute leukemia: a machine learning-based discovery.

Experimental hematology
Allogeneic hematopoietic cell transplantation (allo-HCT) presents a potentially curative treatment for hematologic malignancies yet carries associated risks and complications. Continuous research focuses on predicting outcomes and identifying risk fa...

Why implementing machine learning algorithms in the clinic is not a plug-and-play solution: a simulation study of a machine learning algorithm for acute leukaemia subtype diagnosis.

EBioMedicine
BACKGROUND: Artificial intelligence (AI) and machine learning (ML) algorithms have shown great promise in clinical medicine. Despite the increasing number of published algorithms, most remain unvalidated in real-world clinical settings. This study ai...

An efficient deep learning system for automatic detection of Acute Lymphoblastic Leukemia.

ISA transactions
Early and highly accurate detection of rapidly damaging deadly disease like Acute Lymphoblastic Leukemia (ALL) is essential for providing appropriate treatment to save valuable lives. Recent development in deep learning, particularly transfer learnin...

ALL diagnosis: can efficiency and transparency coexist? An explainble deep learning approach.

Scientific reports
Acute Lymphoblastic Leukemia (ALL) is a life-threatening malignancy characterized by its aggressive progression and detrimental effects on the hematopoietic system. Early and accurate diagnosis is paramount to optimizing therapeutic interventions and...

Explainable transformer-based deep survival analysis in childhood acute lymphoblastic leukemia.

Computers in biology and medicine
BACKGROUND: Acute lymphoblastic leukemia (ALL) is the most common type of leukemia among children and adolescents and can be life-threatening. The incidence of new cases has been increasing in recent years. Developing a predictive model to forecast t...