AIMC Topic: Pregnancy Complications

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Unveiling social determinants of health impact on adverse pregnancy outcomes through natural language processing.

Scientific reports
Understanding the role of Social Determinants of Health (SDoH) in pregnancy outcomes is critical for improving maternal and infant health yet extracting SDoH from unstructured electronic health records remains challenging. We trained and evaluated na...

Intrahepatic cholestasis of pregnancy.

Nature reviews. Disease primers
Intrahepatic cholestasis of pregnancy is the most common pregnancy-related liver disease, manifesting typically during the third trimester of pregnancy with pruritus and elevated serum bile acids. This condition is associated with increased fetal mor...

The role of artificial intelligence in the prediction, identification, diagnosis and treatment of perinatal depression and anxiety among women in LMICs: a systematic review protocol.

BMJ open
INTRODUCTION: Perinatal depression and anxiety (PDA) is associated with a high risk of maternal mortality. Existing data shows that 95% of maternal mortality in low- and middle-income countries (LMICs) is due to resource constraints and negligence in...

Epigenome-wide association study identifies a specific panel of DNA methylation signatures for antenatal and postpartum depressive symptoms.

Journal of affective disorders
Depression during pregnancy and postpartum poses significant risks to both maternal and child well-being. The underlying biological mechanisms are unclear, but epigenetic variation could be exploited as a plausible candidate for early detection. We i...

Leveraging artificial intelligence in the prediction, diagnosis and treatment of depression and anxiety among perinatal women in low- and middle-income countries: a systematic review.

BMJ mental health
AIM: The adoption of artificial intelligence (AI) tools is gaining traction in maternal mental health (MMH) research. Despite its growing usage, little is known about its prospects and challenges in low- and middle-income countries (LMICs). This stud...

Bridging gaps in artificial intelligence adoption for maternal-fetal and obstetric care: Unveiling transformative capabilities and challenges.

Computer methods and programs in biomedicine
PURPOSE: This review aims to comprehensively explore the application of Artificial Intelligence (AI) to an area that has not been traditionally explored in depth: the continuum of maternal-fetal health. In doing so, the intent was to examine this phy...

Prediction of adverse pregnancy outcomes using machine learning techniques: evidence from analysis of electronic medical records data in Rwanda.

BMC medical informatics and decision making
BACKGROUND: Despite substantial progress in maternal and neonatal health, Rwanda's mortality rates remain high, necessitating innovative approaches to meet health related Sustainable Development Goals (SDGs). By leveraging data collected from Electro...

Risk factors and machine learning prediction models for intrahepatic cholestasis of pregnancy.

BMC pregnancy and childbirth
BACKGROUND: Intrahepatic cholestasis of pregnancy (ICP) is a liver disorder that occurs in the second and third trimesters of pregnancy and is associated with a significant risk of fetal complications, including premature birth and fetal death. In cl...

Development and application of a machine learning-based antenatal depression prediction model.

Journal of affective disorders
BACKGROUND: Antenatal depression (AND), occurring during pregnancy, is associated with severe outcomes. However, there is a lack of objective and universally applicable prediction methods for AND in clinical practice. We leveraged sociodemographic an...

Development and validation of a support vector machine-based nomogram for diagnosis of obstetric antiphospholipid syndrome.

Clinica chimica acta; international journal of clinical chemistry
BACKGROUND: Antiphospholipid Syndrome (APS) is a systemic autoimmune disorder characterized by arterial or venous thrombosis and/or pregnancy complications. This study aims to develop a diagnostic model for Obstetric APS (OAPS) using the Support Vect...