AIMC Topic: Antiphospholipid Syndrome

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Development and validation of a support vector machine-based nomogram for diagnosis of obstetric antiphospholipid syndrome.

Clinica chimica acta; international journal of clinical chemistry
BACKGROUND: Antiphospholipid Syndrome (APS) is a systemic autoimmune disorder characterized by arterial or venous thrombosis and/or pregnancy complications. This study aims to develop a diagnostic model for Obstetric APS (OAPS) using the Support Vect...

Mapping Thrombosis Serum Markers by H-NMR Allied with Machine Learning Tools.

Molecules (Basel, Switzerland)
Machine learning and artificial intelligence tools were used to investigate the discriminatory potential of blood serum metabolites for thromboembolism and antiphospholipid syndrome (APS). H-NMR-based metabonomics data of the serum samples of patient...

Characterization of Antiphospholipid Syndrome Atherothrombotic Risk by Unsupervised Integrated Transcriptomic Analyses.

Arteriosclerosis, thrombosis, and vascular biology
OBJECTIVE: Our aim was to characterize distinctive clinical antiphospholipid syndrome phenotypes and identify novel microRNA (miRNA)-mRNA-intracellular signaling regulatory networks in monocytes linked to cardiovascular disease. Approach and Results:...

An Integrated Soft Computing Approach to Hughes Syndrome Risk Assessment.

Journal of medical systems
The AntiPhospholipid Syndrome (APS) is an acquired autoimmune disorder induced by high levels of antiphospholipid antibodies that cause arterial and veins thrombosis, as well as pregnancy-related complications and morbidity, as clinical manifestation...

Antiphospholipid Syndrome with Antiβ2glicoprotein-1 Antibodies as the Cause of Recurrent Tibial Vein Thrombosis in SAPHO syndrome.

Acta dermatovenerologica Croatica : ADC
The antiphospholipid antibody syndrome is defined by the presence of antiphospholipid antibodies in patients with recurrent venous or arterial thromboembolism (1). SAPHO syndrome is a rare disease, characterized by specific clinical manifestations of...