Cervical spinal cord injury (cSCI) poses a significant challenge due to the unpredictable nature of recovery, which ranges from mild paralysis to severe long-term disability. Accurate prognostic models are crucial for guiding treatment and rehabilita...
The objective of this study was to develop and evaluate automated machine learning (aML) models for predicting short-term (1-month) and medium-term (3-month) functional outcomes [Modified Rankin Scale (mRS)] in patients suffering from poor-grade aneu...
BACKGROUND: Accurate prediction of pathologic complete response (pCR) following neoadjuvant immunotherapy combined with chemotherapy (nICT) is crucial for tailoring patient care in esophageal squamous cell carcinoma (ESCC). This study aimed to develo...
PURPOSE: For patients suffering from differentiated thyroid cancer (DTC), several clinical, laboratory, and pathological features (including patient age, tumor size, extrathyroidal extension, or serum thyroglobulin levels) are currently used to ident...
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association
Mar 13, 2025
BACKGROUND: Stroke is a major cause of mortality and permanent disability worldwide. Precise prediction of post-stroke mortality is essential for guiding treatment decisions and rehabilitation planning. The ability of Machine learning models to proce...
Glycolysis is recognized as a central metabolic pathway in the neoplastic evolution of gastric cancer, exerting profound effects on the tumor microenvironment and the neoplastic growth trajectory. However, the identification of key glycolytic genes t...
Cardiac arrest (CA) poses a significant global health challenge and often results in poor prognosis. We developed an interpretable and applicable machine learning (ML) model for predicting in-hospital mortality of CA patients who survived more than 7...
Prostate adenocarcinoma (PAC) is a complex and common cancer in males and is one of the leading causes of cancer-related death globally. PAC is a multifaceted disease that encompasses different subtypes, including acinar and ductal adenocarcinoma, sm...
International journal of molecular sciences
Mar 12, 2025
Chronic myeloid leukemia is a clonal hematologic disease characterized by the presence of the Philadelphia chromosome and the BCR::ABL1 fusion protein. Integrating different molecular, genetic, clinical, and laboratory data would improve the diagnost...
Frontiers in cellular and infection microbiology
Mar 11, 2025
BACKGROUND: Although highly active antiretroviral therapy (HAART) has greatly enhanced the prognosis for people living with HIV (PLWH), some individuals fail to achieve adequate immune reconstitution, known as immunological nonresponse (INR), which i...