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Puberty

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Interpreting IGF-1 in children treated with recombinant growth hormone: challenges during early puberty.

Frontiers in endocrinology
OBJECTIVE: It can be challenging to determine the correct dosage of recombinant growth hormone (GH) in children with GH deficiency, leading to highly variable treatment responses. Insulin-like growth factor-1 (IGF-1) is a tool for monitoring GH treat...

[Determination of polycyclic aromatic hydrocarbons in girls and association between polycyclic aromatic hydrocarbons exposure and puberty timing].

Wei sheng yan jiu = Journal of hygiene research
OBJECTIVE: To develop amethod for simultaneous determination of four metabolites of polycyclic aromatic hydrocarbons( PAHs), and to study the association between puberty timing of girls and PAHs exposure levels in Chongqing.

Association between phthalate exposure and accelerated bone maturation in Chinese girls with early puberty onset: a propensity score-matched case-control analysis.

Scientific reports
Estrogen can promote the acceleration of bone maturation and phthalate esters (PAEs) have estrogen-mimicking effects. We investigated whether PAEs are associated with the acceleration of bone age (BA) in girls with early onset of puberty (EOP). This ...

Olecranon bone age assessment in puberty using a lateral elbow radiograph and a deep-learning model.

European radiology
OBJECTIVES: To improve pubertal bone age (BA) evaluation by developing a precise and practical elbow BA classification using the olecranon, and a deep-learning AI model.

Estimating mandibular growth stage based on cervical vertebral maturation in lateral cephalometric radiographs using artificial intelligence.

Progress in orthodontics
INTRODUCTION: Determining the right time for orthodontic treatment is one of the most important factors affecting the treatment plan and its outcome. The aim of this study is to estimate the mandibular growth stage based on cervical vertebral maturat...