AIMC Topic: Radiotherapy Dosage

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A hierarchical deep reinforcement learning framework for intelligent automatic treatment planning of prostate cancer intensity modulated radiation therapy.

Physics in medicine and biology
We have previously proposed an intelligent automatic treatment planning (IATP) framework that builds a virtual treatment planner network (VTPN) to operate a treatment planning system (TPS) to generate high-quality radiation therapy (RT) treatment pla...

Technical Note: Dose prediction for head and neck radiotherapy using a three-dimensional dense dilated U-net architecture.

Medical physics
PURPOSE: Radiation therapy treatment planning is a time-consuming and iterative manual process. Consequently, plan quality varies greatly between and within institutions. Artificial intelligence shows great promise in improving plan quality and reduc...

Technical Note: Dose prediction for radiation therapy using feature-based losses and One Cycle Learning.

Medical physics
PURPOSE: To present the technical details of the runner-up model in the open knowledge-based planning (OpenKBP) challenge for the dose-volume histogram (DVH) stream. The model was designed to ensure simple and reproducible training, without the neces...

Independent verification of brachytherapy treatment plan by using deep learning inference modeling.

Physics in medicine and biology
This study aims to develop a deep learning-based strategy for treatment plan check and verification of high-dose rate (HDR) brachytherapy. A deep neural network was trained to verify the dwell positions and times for a given input brachytherapy isodo...

Implementation of deep learning-based auto-segmentation for radiotherapy planning structures: a workflow study at two cancer centers.

Radiation oncology (London, England)
PURPOSE: We recently described the validation of deep learning-based auto-segmented contour (DC) models for organs at risk (OAR) and clinical target volumes (CTV). In this study, we evaluate the performance of implemented DC models in the clinical ra...

Clinical validation of a commercially available deep learning software for synthetic CT generation for brain.

Radiation oncology (London, England)
BACKGROUND: Most studies on synthetic computed tomography (sCT) generation for brain rely on in-house developed methods. They often focus on performance rather than clinical feasibility. Therefore, the aim of this work was to validate sCT images gene...

AAPM Task Group 264: The safe clinical implementation of MLC tracking in radiotherapy.

Medical physics
The era of real-time radiotherapy is upon us. Robotic and gimbaled linac tracking are clinically established technologies with the clinical realization of couch tracking in development. Multileaf collimators (MLCs) are a standard equipment for most c...

Radiation therapy dose prediction for left-sided breast cancers using two-dimensional and three-dimensional deep learning models.

Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB)
PURPOSE: To develop a deep learning model capable of producing clinically acceptable dose distributions for left-sided breast cancers for 3D-CRT while exploring the use of two-dimensional versus three-dimensional anatomical data.

Computation of epistemic uncertainty due to limited data samples in small field dosimetry using Fuzzy Set Theory.

The British journal of radiology
OBJECTIVE: To estimate the epistemic (or fuzzy) uncertainty, arising due to limited data samples in the measurement of the output factors (OFs) of the small fields using Fuzzy Set Theory (FST).