Synthesizing computed tomography (CT) images from magnetic resonance imaging (MRI) data can provide the necessary electron density information for accurate dose calculation in the treatment planning of MRI-guided radiation therapy (MRIgRT). Inputting...
Biomedical physics & engineering express
May 12, 2023
Proton therapy is a type of radiation therapy that can provide better dose distribution compared to photon therapy by delivering most of the energy at the end of range, which is called the Bragg peak (BP). The protoacoustic technique was developed to...
Accurate and efficient delineation of the clinical target volume (CTV) is of utmost significance in post-operative breast cancer radiotherapy. However, CTV delineation is challenging as the exact extent of microscopic disease encompassed by CTV is no...
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
May 6, 2023
BACKGROUND AND PURPOSE: Magnetic Resonance (MR)-only radiotherapy enables the use of MR without the uncertainty of MR-Computed Tomography (CT) registration. This requires a synthetic CT (sCT) for dose calculations, which can be facilitated by a novel...
. Adaptive radiotherapy workflows require images with the quality of computed tomography (CT) for re-calculation and re-optimisation of radiation doses. In this work we aim to improve the quality of on-board cone beam CT (CBCT) images for dose calcul...
BACKGROUND: In cancer care, determining the most beneficial treatment technique is a key decision affecting the patient's survival and quality of life. Patient selection for proton therapy (PT) over conventional radiotherapy (XT) currently entails co...
Journal of applied clinical medical physics
May 3, 2023
PURPOSE: In this paper, we compare four novel knowledge-based planning (KBP) algorithms using deep learning to predict three-dimensional (3D) dose distributions of head and neck plans using the same patients' dataset and quantitative assessment metri...
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
Apr 28, 2023
PURPOSE: We previously developed a virtual treatment planner (VTP), an artificial intelligence robot, operating a treatment planning system (TPS). Using deep reinforcement learning guided by human knowledge, we trained the VTP to autonomously adjust ...
. Robustness evaluation is critical in particle radiotherapy due to its susceptibility to uncertainties. However, the customary method for robustness evaluation only considers a few uncertainty scenarios, which are insufficient to provide a consisten...
. CBCTs in image-guided radiotherapy provide crucial anatomy information for patient setup and plan evaluation. Longitudinal CBCT image registration could quantify the inter-fractional anatomic changes, e.g. tumor shrinkage, and daily OAR variation t...
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