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Radiotherapy Planning, Computer-Assisted

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Efficient dose-volume histogram-based pretreatment patient-specific quality assurance methodology with combined deep learning and machine learning models for volumetric modulated arc radiotherapy.

Medical physics
BACKGROUND: Weak correlation between gamma passing rates and dose differences in target volumes and organs at risk (OARs) has been reported in several studies. Evaluation on the differences between planned dose-volume histogram (DVH) and reconstructe...

Predictive gamma passing rate of 3D detector array-based volumetric modulated arc therapy quality assurance for prostate cancer via deep learning.

Physical and engineering sciences in medicine
To predict the gamma passing rate (GPR) of the three-dimensional (3D) detector array-based volumetric modulated arc therapy (VMAT) quality assurance (QA) for prostate cancer using a convolutional neural network (CNN) with the 3D dose distribution. On...

A plan verification platform for online adaptive proton therapy using deep learning-based Monte-Carlo denoising.

Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB)
BACKGROUND PURPOSE: This study focused on developing a fast Monte Carlo (MC) plan verification platform via a deep learning (DL)-based denoising approach. It can maintain the MC dose calculation accuracy while significantly reducing the computation t...

An uncertainty-aware deep learning architecture with outlier mitigation for prostate gland segmentation in radiotherapy treatment planning.

Medical physics
PURPOSE: Task automation is essential for efficient and consistent image segmentation in radiation oncology. We report on a deep learning architecture, comprising a U-Net and a variational autoencoder (VAE) for automatic contouring of the prostate gl...

Automated clinical decision support system with deep learning dose prediction and NTCP models to evaluate treatment complications in patients with esophageal cancer.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
BACKGROUND AND PURPOSE: This study aims to investigate how accurate our deep learning (DL) dose prediction models for intensity modulated radiotherapy (IMRT) and pencil beam scanning (PBS) treatments, when chained with normal tissue complication prob...

Clinical evaluation of deep learning and atlas-based auto-segmentation for critical organs at risk in radiation therapy.

Journal of medical radiation sciences
INTRODUCTION: Contouring organs at risk (OARs) is a time-intensive task that is a critical part of radiation therapy. Atlas-based automatic segmentation has shown some success at reducing this time burden on practitioners; however, this method often ...

Auto-segmentation of important centers of growth in the pediatric skeleton to consider during radiation therapy based on deep learning.

Medical physics
BACKGROUND: Routinely delineating of important skeletal growth centers is imperative to mitigate radiation-induced growth abnormalities for pediatric cancer patients treated with radiotherapy. However, it is hindered by several practical problems, in...

A deep learning approach to generate synthetic CT in low field MR-guided radiotherapy for lung cases.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
INTRODUCTION: This study aims to apply a conditional Generative Adversarial Network (cGAN) to generate synthetic Computed Tomography (sCT) from 0.35 Tesla Magnetic Resonance (MR) images of the thorax.

Artificial intelligence in radiotherapy.

Seminars in cancer biology
Radiotherapy is a discipline closely integrated with computer science. Artificial intelligence (AI) has developed rapidly over the past few years. With the explosive growth of medical big data, AI promises to revolutionize the field of radiotherapy t...

Development of deep learning chest X-ray model for cardiac dose prediction in left-sided breast cancer radiotherapy.

Scientific reports
Deep inspiration breath-hold (DIBH) is widely used to reduce the cardiac dose in left-sided breast cancer radiotherapy. This study aimed to develop a deep learning chest X-ray model for cardiac dose prediction to select patients with a potentially hi...