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Randomized Controlled Trials as Topic

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ognitive utcomes in the ragmatic nvestigation of optimaxygen argets (CO-PILOT) trial: protocol and statistical analysis plan.

BMJ open
INTRODUCTION: Long-term cognitive impairment is one of the most common complications of critical illness among survivors who receive mechanical ventilation. Recommended oxygen targets during mechanical ventilation vary among international guidelines....

Machine learning algorithms to identify cluster randomized trials from MEDLINE and EMBASE.

Systematic reviews
BACKGROUND: Cluster randomized trials (CRTs) are becoming an increasingly important design. However, authors of CRTs do not always adhere to requirements to explicitly identify the design as cluster randomized in titles and abstracts, making retrieva...

Machine learning for detecting centre-level irregularities in randomized controlled trials: A pilot study.

Contemporary clinical trials
Centralized statistical monitoring is sometimes employed as an alternative to onsite monitoring for randomized control trials. Current central monitoring methods have limitations, in that they are relatively resource intensive and do not necessarily ...

Implementation of machine learning in the clinic: challenges and lessons in prospective deployment from the System for High Intensity EvaLuation During Radiation Therapy (SHIELD-RT) randomized controlled study.

BMC bioinformatics
BACKGROUND: Artificial intelligence (AI) and machine learning (ML) have resulted in significant enthusiasm for their promise in healthcare. Despite this, prospective randomized controlled trials and successful clinical implementation remain limited. ...

Effect and safety of diluted vasopressin injection on bleeding during robot-assisted laparoscopic myomectomy: a protocol for a randomised controlled pilot trial.

BMJ open
INTRODUCTION: Even though the injection of diluted vasopressin into the uterus is expected to reduce intraoperative bleeding with decreased adverse effects during robot-assisted laparoscopic myomectomy (RALM), there is a lack of relevant trials to sh...

Spinal robotics in cervical spine surgery: a systematic review with key concepts and technical considerations.

Journal of neurosurgery. Spine
OBJECTIVE: Spinal robotics for thoracolumbar procedures, predominantly employed for the insertion of pedicle screws, is currently an emerging topic in the literature. The use of robotics in instrumentation of the cervical spine has not been broadly e...

Quality of reporting of randomised controlled trials of artificial intelligence in healthcare: a systematic review.

BMJ open
OBJECTIVES: The aim of this study was to evaluate the quality of reporting of randomised controlled trials (RCTs) of artificial intelligence (AI) in healthcare against Consolidated Standards of Reporting Trials-AI (CONSORT-AI) guidelines.

Randomized Clinical Trials of Machine Learning Interventions in Health Care: A Systematic Review.

JAMA network open
IMPORTANCE: Despite the potential of machine learning to improve multiple aspects of patient care, barriers to clinical adoption remain. Randomized clinical trials (RCTs) are often a prerequisite to large-scale clinical adoption of an intervention, a...

Randomized Controlled Trials of Artificial Intelligence in Clinical Practice: Systematic Review.

Journal of medical Internet research
BACKGROUND: The number of artificial intelligence (AI) studies in medicine has exponentially increased recently. However, there is no clear quantification of the clinical benefits of implementing AI-assisted tools in patient care.

Effectiveness of robot-assisted virtual reality mirror therapy for upper limb motor dysfunction after stroke: study protocol for a single-center randomized controlled clinical trial.

BMC neurology
BACKGROUND: Upper limb motor dysfunction is a common sequela of stroke, and its clinical efficacy needs to be improved. This protocol describes a trial to verify the clinical efficacy of robot-assisted virtual reality mirror therapy (RAVRMT) in impro...