Research on an early detection of Mild Cognitive Impairment (MCI), a prodromal stage of Alzheimer's Disease (AD), with resting-state functional Magnetic Resonance Imaging (rs-fMRI) has been of great interest for the last decade. Witnessed by recent s...
PURPOSE: The treatment of thoracic cancer using external beam radiation requires an optimal selection of the radiation beam directions to ensure effective coverage of the target volume and to avoid unnecessary treatment of normal healthy tissues. Int...
Methods of construction of support vector machines do not require additional a priori information and can be used to process large scale data set. It is especially important for various problems in computational biology. The main set of algorithms of...
Journal of Nippon Medical School = Nippon Ika Daigaku zasshi
Jan 1, 2015
BACKGROUND: Relationships between various climate factors and stroke have long been a subject of investigation. The present study investigated in a single medical center the effects of periodic temperature changes on the onset of intracerebral hemorr...
Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
Jan 1, 2015
This paper presents a novel patient-specific algorithm for detection of seizures in epileptic patients with low hardware complexity and low power consumption. In the proposed approach, we first compute the spectrogram of the input fragmented EEG sign...
International journal of data mining and bioinformatics
Jan 1, 2015
In silico prediction of novel miRNAs from genomic sequences remains a challenging problem. This study presents a genome-wide miRNA discovery software package called GenoScan and evaluates two hairpin classification methods. These methods, one ensembl...
Applications of neural machine interfaces have received increased attention during the last decades. It is crucial to realize the continuous control of prosthetic devices based on biological signals. In order to deal with the highly nonlinear relatio...
Premature ventricular contraction (PVC) is one of the most serious arrhythmias. Without early diagnosis and proper treatment, PVC can result in significant complications. In this paper, a novel feature extraction method based on a sparse auto-encoder...
Journal of enzyme inhibition and medicinal chemistry
Jan 1, 2015
The aim of this study is to propose an improved computational methodology, which is called Compressed Images for Affinity Prediction-2 (CIFAP-2) to predict binding affinities of structurally related protein-ligand complexes. CIFAP-2 method is establi...
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