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Schizophrenia

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GENEVIC: GENetic data Exploration and Visualization via Intelligent interactive Console.

Bioinformatics (Oxford, England)
SUMMARY: The vast generation of genetic data poses a significant challenge in efficiently uncovering valuable knowledge. Introducing GENEVIC, an AI-driven chat framework that tackles this challenge by bridging the gap between genetic data generation ...

Wavelet Transform, Reconstructed Phase Space, and Deep Learning Neural Networks for EEG-Based Schizophrenia Detection.

International journal of neural systems
This study proposes an innovative expert system that uses exclusively EEG signals to diagnose schizophrenia in its early stages. For diagnosing psychiatric/neurological disorders, electroencephalogram (EEG) testing is considered a financially viable,...

Detecting outliers in case-control cohorts for improving deep learning networks on Schizophrenia prediction.

Journal of integrative bioinformatics
This study delves into the intricate genetic and clinical aspects of Schizophrenia, a complex mental disorder with uncertain etiology. Deep Learning (DL) holds promise for analyzing large genomic datasets to uncover new risk factors. However, based o...

Forecasting the incidence frequencies of schizophrenia using deep learning.

Asian journal of psychiatry
Mental disorders are becoming increasingly prevalent worldwide, and accurate incidence forecasting is crucial for effective mental health strategies. This study developed a long short-term memory (LSTM)-based recurrent neural network model to predict...

Assessing dimensions of thought disorder with large language models: The tradeoff of accuracy and consistency.

Psychiatry research
Natural Language Processing (NLP) methods have shown promise for the assessment of formal thought disorder, a hallmark feature of schizophrenia in which disturbances to the structure, organization, or coherence of thought can manifest as disordered o...

Schizophrenia diagnosis using the GRU-layer's alpha-EEG rhythm's dependability.

Psychiatry research. Neuroimaging
Verifying schizophrenia (SZ) can be assisted by deep learning techniques and patterns in brain activity observed in alpha-EEG recordings. The suggested research provides evidence of the reliability of alpha-EEG rhythm in a Gated-Recurrent-Unit-based ...

CNVDeep: deep association of copy number variants with neurocognitive disorders.

BMC bioinformatics
BACKGROUND: Copy number variants (CNVs) have become increasingly instrumental in understanding the etiology of all diseases and phenotypes, including Neurocognitive Disorders (NDs). Among the well-established regions associated with ND are small part...

Immune-based Machine learning Prediction of Diagnosis and Illness State in Schizophrenia and Bipolar Disorder.

Brain, behavior, and immunity
BACKGROUND: Schizophrenia and bipolar disorder frequently face significant delay in diagnosis, leading to being missed or misdiagnosed in early stages. Both disorders have also been associated with trait and state immune abnormalities. Recent machine...

Enhancing schizophrenia phenotype prediction from genotype data through knowledge-driven deep neural network models.

Genomics
This article explores deep learning model design, drawing inspiration from the omnigenic model and genetic heterogeneity concepts, to improve schizophrenia prediction using genotype data. It introduces an innovative three-step approach leveraging neu...

Identification of Immune-Related Biomarkers of Schizophrenia in the Central Nervous System Using Bioinformatic Methods and Machine Learning Algorithms.

Molecular neurobiology
Schizophrenia is a disastrous mental disorder. Identification of diagnostic biomarkers and therapeutic targets is of significant importance. In this study, five datasets of schizophrenia post-mortem prefrontal cortex samples were downloaded from the ...