AIMC Topic: Sepsis

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An approach to rapidly assess sepsis through multi-biomarker host response using machine learning algorithm.

Scientific reports
Sepsis is a life-threatening condition and understanding the disease pathophysiology through the use of host immune response biomarkers is critical for patient stratification. Lack of accurate sepsis endotyping impedes clinicians from making timely d...

Kinematics approach with neural networks for early detection of sepsis (KANNEDS).

BMC medical informatics and decision making
BACKGROUND: Sepsis is a severe illness that affects millions of people worldwide, and its early detection is critical for effective treatment outcomes. In recent years, researchers have used models to classify positive patients or identify the probab...

Comparison of machine-learning methodologies for accurate diagnosis of sepsis using microarray gene expression data.

PloS one
We investigate the feasibility of molecular-level sample classification of sepsis using microarray gene expression data merged by in silico meta-analysis. Publicly available data series were extracted from NCBI Gene Expression Omnibus and EMBL-EBI Ar...

A predictive framework in healthcare: Case study on cardiac arrest prediction.

Artificial intelligence in medicine
Data-driven healthcare uses predictive analytics to enhance decision-making and personalized healthcare. Developing prognostic models is one of the applications of predictive analytics in medical environments. Various studies have used machine learni...

Diagnostic and prognostic capabilities of a biomarker and EMR-based machine learning algorithm for sepsis.

Clinical and translational science
Sepsis is a major cause of mortality among hospitalized patients worldwide. Shorter time to administration of broad-spectrum antibiotics is associated with improved outcomes, but early recognition of sepsis remains a major challenge. In a two-center ...

Role of Artificial Intelligence Applications in Real-Life Clinical Practice: Systematic Review.

Journal of medical Internet research
BACKGROUND: Artificial intelligence (AI) applications are growing at an unprecedented pace in health care, including disease diagnosis, triage or screening, risk analysis, surgical operations, and so forth. Despite a great deal of research in the dev...

Physiological machine learning models for prediction of sepsis in hospitalized adults: An integrative review.

Intensive & critical care nursing
BACKGROUND: Diagnosing sepsis remains challenging. Data compiled from continuous monitoring and electronic health records allow for new opportunities to compute predictions based on machine learning techniques. There has been a lack of consensus iden...

Preventing sepsis; how can artificial intelligence inform the clinical decision-making process? A systematic review.

International journal of medical informatics
BACKGROUND AND OBJECTIVES: Sepsis is a life-threatening condition that is associated with increased mortality. Artificial intelligence tools can inform clinical decision making by flagging patients at risk of developing infection and subsequent sepsi...

Development and Validation of a Machine Learning Model to Estimate Bacterial Sepsis Among Immunocompromised Recipients of Stem Cell Transplant.

JAMA network open
IMPORTANCE: Sepsis disproportionately affects recipients of allogeneic hematopoietic cell transplant (allo-HCT), and timely detection is crucial. However, the atypical presentation of sepsis within this population makes detection challenging, and exi...