AIMC Topic: Software

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ODIASP: An Open-Source Software for Automated SMI Determination-Application to an Inpatient Population.

Journal of cachexia, sarcopenia and muscle
BACKGROUND: The diagnosis of malnutrition has evolved with the GLIM recommendations, which advocate for integrating phenotypic criteria, including muscle mass measurement. The GLIM framework specifically suggests using skeletal muscle index (SMI) ass...

DSSP 4: FAIR annotation of protein secondary structure.

Protein science : a publication of the Protein Society
Protein secondary structure annotation is essential for understanding protein architecture, serving as a cornerstone for structural classification, alignment, visualization, and machine learning applications. The Define Secondary Structure of Protein...

PEGASUS: Prediction of MD-derived protein flexibility from sequence.

Protein science : a publication of the Protein Society
Protein flexibility is essential to its biological function. However, experimental methods for its assessment, such as X-ray crystallography and nuclear magnetic resonance spectroscopy, are often limited by experimental variability and high cost, lea...

HAIRpred: Prediction of human antibody interacting residues in an antigen from its primary structure.

Protein science : a publication of the Protein Society
In the past, several methods have been developed for predicting conformational B-cell epitopes in antigens that are not specific to any host. Our primary analysis of antibody-antigen complexes indicated a need to develop host-specific B-cell epitopes...

A large language model for predicting neurotoxic peptides and neurotoxins.

Protein science : a publication of the Protein Society
The accurate prediction of neurotoxicity in peptides and proteins is essential for the safety evaluation of therapeutic proteins and genetically modified (GM) organisms. Existing tools, including our earlier method NTxPred, typically use a single pre...

The Future of a Myriad of Accelerated Biodiscoveries Lies in AI-Powered Mass Spectrometry and Multiomics Integration.

Journal of mass spectrometry : JMS
The intersection of modern artificial intelligence (AI) and mass spectrometry (MS) is set to transform the MS-based "omics" research fields, particularly proteomics, metabolomics, lipidomics, and glycomics, enabling advancements across a wide range o...

ADEPT: An advanced data exploration and processing tool for clinical data insights.

Computer methods and programs in biomedicine
BACKGROUND AND OBJECTIVE: The rapid growth of clinical data creates challenges in analysis and interpretation for medical professionals. To address these issues, we developed the Advanced Data Exploration and Processing Tool (ADEPT), integrating data...

Morphological effects of input data quantity in AI-powered dental crown design.

Journal of dentistry
OBJECTIVES: This retrospective in vitro study evaluated the impact of input data quantity on the morphology of dental crowns generated by AI-based software. The hypothesis suggests that increased input data quantity improves the quality of generated ...

Patient prioritization for pharmaceutical intervention in the hospital setting: a retrospective cross-sectional study.

The International journal of pharmacy practice
OBJECTIVES: Prioritization of patients requiring pharmaceutical intervention is critical given limited resources. Data from pharmacy software could be used to target patients. This retrospective cross-sectional study aimed to describe the method impl...

ModiDeC: a multi-RNA modification classifier for direct nanopore sequencing.

Nucleic acids research
RNA modifications play a crucial role in various cellular functions. Here, we present ModiDeC, a deep-learning-based classifier able to identify and distinguish multiple RNA modifications (N6-methyladenosine, inosine, pseudouridine, 2'-O-methylguanos...