AIMC Topic: Software

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Prediction of Clinical Events in Hemodialysis Patients Using an Artificial Neural Network.

Studies in health technology and informatics
Advanced chronic kidney disease (CKD) requires routine renal replacement therapy (RRT) that involves hemodialysis (HD) which may cause increased risk of muscle spasms, cardiovascular events, and death. We used Artificial Neural Network (ANN) method t...

Demand Analysis and Function Design of Health Decision Support System in China.

Studies in health technology and informatics
In order to improve the level of health decision-making, based on health information resources and decision support function types, this study summarized five core functions of health decision support system: information support, monitoring and early...

DeepPhos: prediction of protein phosphorylation sites with deep learning.

Bioinformatics (Oxford, England)
MOTIVATION: Phosphorylation is the most studied post-translational modification, which is crucial for multiple biological processes. Recently, many efforts have been taken to develop computational predictors for phosphorylation site prediction, but m...

Open Source Infrastructure for Health Care Data Integration and Machine Learning Analyses.

JCO clinical cancer informatics
PURPOSE: We have created a cloud-based machine learning system (CLOBNET) that is an open-source, lean infrastructure for electronic health record (EHR) data integration and is capable of extract, transform, and load (ETL) processing. CLOBNET enables ...

Obtaining Knowledge in Pathology Reports Through a Natural Language Processing Approach With Classification, Named-Entity Recognition, and Relation-Extraction Heuristics.

JCO clinical cancer informatics
PURPOSE: Robust institutional tumor banks depend on continuous sample curation or else subsequent biopsy or resection specimens are overlooked after initial enrollment. Curation automation is hindered by semistructured free-text clinical pathology no...

Systematic selection of chemical fingerprint features improves the Gibbs energy prediction of biochemical reactions.

Bioinformatics (Oxford, England)
MOTIVATION: Accurate and wide-ranging prediction of thermodynamic parameters for biochemical reactions can facilitate deeper insights into the workings and the design of metabolic systems.

PconsC4: fast, accurate and hassle-free contact predictions.

Bioinformatics (Oxford, England)
MOTIVATION: Residue contact prediction was revolutionized recently by the introduction of direct coupling analysis (DCA). Further improvements, in particular for small families, have been obtained by the combination of DCA and deep learning methods. ...

BioSeq-Analysis: a platform for DNA, RNA and protein sequence analysis based on machine learning approaches.

Briefings in bioinformatics
With the avalanche of biological sequences generated in the post-genomic age, one of the most challenging problems is how to computationally analyze their structures and functions. Machine learning techniques are playing key roles in this field. Typi...

Rotation equivariant and invariant neural networks for microscopy image analysis.

Bioinformatics (Oxford, England)
MOTIVATION: Neural networks have been widely used to analyze high-throughput microscopy images. However, the performance of neural networks can be significantly improved by encoding known invariance for particular tasks. Highly relevant to the goal o...

Computational functional genomics-based reduction of disease-related gene sets to their key components.

Bioinformatics (Oxford, England)
MOTIVATION: The genetic architecture of diseases becomes increasingly known. This raises difficulties in picking suitable targets for further research among an increasing number of candidates. Although expression based methods of gene set reduction a...