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Specimen Handling

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Comparison of the Bone Harvesting Capacity of an Intraoral Bone Harvesting Device and Three Different Implant Drills.

BioMed research international
The aim of the present study was to compare bone-collecting capacity of bone harvesting device and minimally irrigated low-speed drilling using three implant systems. One bone harvesting device and three commercially available drill systems were comp...

Collection of Post-mating Semen from the Female Reproductive Tract and Measurement of Semen Liquefaction in Mice.

Journal of visualized experiments : JoVE
In mice, ejaculated semen is deposited in the uterus. After ejaculation, the semen changes consistency from gel-like to watery, a process called liquefaction. In this study, we show how to collect the post-ejaculated semen from the female reproductiv...

Automation of the Differential Digestion Process of Sexual Assault Evidence.

Journal of forensic sciences
Sexual assault evidence samples require the use of a specific process known as a differential digestion to separate sperm from nonsperm cells prior to DNA extraction. An automated differential digestion process was developed using a selective degrada...

Evaluation of the VITEK MS knowledge base version 3.0 for the identification of clinically relevant Mycobacterium species.

Emerging microbes & infections
Different Mycobacterium spp. infections may indicate varied treatment regimens in the clinic. Thus, the species-level identification of Mycobacterium spp. is one of the most important tasks for a clinical microbiology laboratory. Although matrix-assi...

Automated Analytical Measurement Processes Using a Dual-Arm Robotic System.

SLAS technology
The demand for automation in the analytical laboratory is high. In contrast to well-automated bioscreening and high-throughput and high-content screening processes, analytical measurement procedures are complex in their structure and changing frequen...

Automation of the standard DNA differential extraction on the Hamilton AutoLys STAR system: A proof-of-concept study.

Forensic science international. Genetics
For several decades, a common approach for processing sexual assault evidence has been to use the "standard" differential extraction to separate the evidence into a non-sperm-cell fraction and a sperm-cell fraction for further analysis. In this stand...

A low-cost, automated parasite diagnostic system via a portable, robotic microscope and deep learning.

Journal of biophotonics
Manual hand counting of parasites in fecal samples requires costly components and substantial expertise, limiting its use in resource-constrained settings and encouraging overuse of prophylactic medication. To address this issue, a cost-effective, au...

Purification of viable peripheral blood mononuclear cells for biobanking using a robotized liquid handling workstation.

Journal of translational medicine
BACKGROUND: The purification of peripheral blood mononuclear cells (PBMCs) by means of density gradient (1.07 g/mL) centrifugation is one of the most commonly used methods in diagnostics and research laboratories as well as in biobanks. Here, we eval...

Highly accurate and explainable detection of specimen mix-up using a machine learning model.

Clinical chemistry and laboratory medicine
Background Delta check is widely used for detecting specimen mix-ups. Owing to the inadequate specificity and sparseness of the absolute incidence of mix-ups, the positive predictive value (PPV) of delta check is considerably low as it is labor consu...

Ultra-gentle soft robotic fingers induce minimal transcriptomic response in a fragile marine animal.

Current biology : CB
Tessler et al. demonstrate that a 'soft' robot causes less stress to a jellyfish while handling compared to a traditional 'hard' robot.