AIMC Topic: Spheroids, Cellular

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Endoscopy-assisted magnetic navigation of biohybrid soft microrobots with rapid endoluminal delivery and imaging.

Science robotics Mar 17, 2021
High-precision delivery of microrobots at the whole-body scale is of considerable importance for efforts toward targeted therapeutic intervention. However, vision-based control of microrobots, to deep and narrow spaces inside the body, remains a chal...
Humans Female Endoscopy Drug Delivery Systems Animals Male Computer Systems Ultrasonography Mice Rats Rats, Sprague-Dawley Robotics Diagnostic Imaging Equipment Design Microtechnology 3T3 Cells Microscopy, Electron, Scanning Magnetics Sus scrofa Spheroids, Cellular Natural Orifice Endoscopic Surgery
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Deep-LUMEN assay - human lung epithelial spheroid classification from brightfield images using deep learning.

Lab on a chip Dec 15, 2020
Three-dimensional (3D) tissue models such as epithelial spheroids or organoids have become popular for pre-clinical drug studies. In contrast to 2D monolayer culture, the characterization of 3D tissue models from non-invasive brightfield images is a ...
Humans Lung Deep Learning Spheroids, Cellular Organoids
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Deep learning guided image-based droplet sorting for on-demand selection and analysis of single cells and 3D cell cultures.

Lab on a chip Mar 3, 2020
Uncovering the heterogeneity of cellular populations and multicellular constructs is a long-standing goal in fields ranging from antimicrobial resistance to cancer research. Emerging technology platforms such as droplet microfluidics hold the promise...
Animals Deep Learning Cell Movement Microfluidics Cell Culture Techniques Spheroids, Cellular
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Robotic printing and drug testing of 384-well tumor spheroids.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference Aug 1, 2015
A major impediment to anti-cancer drug development is the lack of a reliable and inexpensive tumor model to test the efficacy of candidate compounds. This need has emerged due to the insufficiency of widely-used monolayer cultures to predict drug eff...
Humans Female Antineoplastic Agents Triple Negative Breast Neoplasms Drug Screening Assays, Antitumor Robotics Equipment Design Polymers Doxorubicin High-Throughput Screening Assays Spheroids, Cellular
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