AIMC Topic: Substance Abuse Detection
Clear Filters Showing 11 to 19 of 19 articles
An Approach to Biomarker Discovery of Cannabis Use Utilizing Proteomic, Metabolomic, and Lipidomic Analyses.
Cannabis and cannabinoid research
Jun 19, 2020
Relatively little is known about the molecular pathways influenced by cannabis use in humans. We used a multi-omics approach to examine protein, metabolomic, and lipid markers in plasma differentiating between cannabis users and nonusers to understa...
A machine learning approach for handling big data produced by high resolution mass spectrometry after data independent acquisition of small molecules - Proof of concept study using an artificial neural network for sample classification.
Drug testing and analysis
Feb 6, 2020
Liquid chromatography coupled to high-resolution mass spectrometry (HRMS) enables data independent acquisition (DIA) and untargeted screening. However, to avoid the handling of the resulting large dataset, most laboratories in that field still use ta...
On-site testing of multiple drugs of abuse in urine by a miniature dual-LIT mass spectrometer.
Analytica chimica acta
Dec 13, 2019
There is an increasing need for rapid and on-site detection of emerging drugs of abuse. In this work, we developed a method using a miniature dual-LIT (linear ion trap) mass spectrometer recently developed with comprehensive tandem mass spectrometry ...
Deep Learning-Assisted Three-Dimensional Fluorescence Difference Spectroscopy for Identification and Semiquantification of Illicit Drugs in Biofluids.
Analytical chemistry
Jun 13, 2019
The fast identification and quantification of illicit drugs in biofluids are of great significance in clinical detection. However, existing drug detection strategies cannot fully meet clinical needs, and the on-site identification and quantification ...
Quantitative analysis of desomorphine in blood and urine using solid phase extraction and gas chromatography-mass spectrometry.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences
Dec 18, 2018
Desomorphine, a semi-synthetic opioid, is a component of the street drug Krokodil. Despite continued reports of Krokodil use, confirmation via toxicological testing remains scarce. The lack of confirmed desomorphine reports may be in part due to the ...
Using Neural Multi-task Learning to Extract Substance Abuse Information from Clinical Notes.
AMIA ... Annual Symposium proceedings. AMIA Symposium
Dec 5, 2018
Substance abuse carries many negative health consequences. Detailed information about patients' substance abuse history is usually captured in free-text clinical notes. Automatic extraction of substance abuse information is vital to assess patients' ...
[Identification of Methamphetamine Abuse and Selegiline Use： Chiral Analysis of Methamphetamine and Amphetamine in Urine].
Fa yi xue za zhi
Dec 25, 2017
OBJECTIVES: To study the content variation of selegiline and its metabolites in urine, and based on actual cases, to explore the feasibility for the identification of methamphetamine abuse and selegiline use by chiral analysis.
Forecasting Banned Substances: Leveraging GNN and Explainable AI for Sports Anti-Doping.
Studies in health technology and informatics
May 15, 2025
Ensuring fairness in competitive sports requires robust mechanisms for detecting prohibited substances. Despite established regulations, challenges persist in accurately identifying new and emerging doping agents. This study introduces the use of Gra...
Enhancing Risk Assessment in Patients Receiving Chronic Opioid Analgesic Therapy Using Natural Language Processing.
Pain medicine (Malden, Mass.)
Oct 1, 2017
OBJECTIVES: Clinical guidelines for the use of opioids in chronic noncancer pain recommend assessing risk for aberrant drug-related behaviors prior to initiating opioid therapy. Despite recent dramatic increases in prescription opioid misuse and abus...
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