Pathway analysis plays a critical role in bioinformatics, enabling researchers to identify biological pathways associated with various conditions by analyzing gene expression data. However, the rise of large, multi-center datasets has highlighted lim...
Small sample sizes in biomedical research often led to poor reproducibility and challenges in translating findings into clinical applications. This problem stems from limited study resources, rare diseases, ethical considerations in animal studies, c...
Brain neural signal at different frequency bands relates to different functions. However, the frequency-specific properties of spontaneous brain activity in tension-type headache (TTH)-the most rampant primary headache-remain largely unknown. We inve...
BACKGROUND: Schizophrenia is a complex and disabling mental disorder that represents one of the most important challenges for neuroimaging research. There were many attempts to understand these basic mechanisms behind the disorder, yet we know very l...
Studies in health technology and informatics
Aug 30, 2024
INTRODUCTION: Human and veterinary medicine are practiced separately, but literature databases such as Pubmed include articles from both fields. This impedes supporting clinical decisions with automated information retrieval, because treatment consid...
Ischemic stroke (IS) has a high recurrence rate. Machine learning (ML) models have been developed based on single-modal biochemical tests, and imaging data have been used to predict stroke recurrence. However, the prediction accuracy of these models ...
Studies in health technology and informatics
Aug 22, 2024
Multi-objective optimization holds particular significance for medical applications, wherein enhancing sensitivity is crucial to avoid costly missed diagnoses, and maintaining high specificity is imperative to prevent unnecessary procedures. In parti...
Studies in health technology and informatics
Aug 22, 2024
Type 2 Diabetes (T2D) is a prevalent lifelong health condition. It is predicted that over 500 million adults will be diagnosed with T2D by 2040. T2D can develop at any age, and if it progresses, it may cause serious comorbidities. One of the most cri...
Soil heavy metal pollution poses a serious threat to food security, human health, and soil ecosystems. Based on 644 soil samples collected from a typical oasis located at the eastern margin of the Tarim Basin, a series of models, namely, multiple lin...
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