Post-translational modifications (PTMs) are fundamental to essential biological processes, exerting significant influence over gene expression, protein localization, stability, and genome replication. Sumoylation, a PTM involving the covalent additio...
BACKGROUND: Small clinics are important in providing health care in local communities. Accurately predicting their closure would help manage health care resource allocation. There have been few studies on the prediction of clinic closure using machin...
A stroke is a dangerous, life-threatening disease that mostly affects people over 65, but an unhealthy diet is also contributing to the development of strokes at younger ages. Strokes can be treated successfully if they are identified early enough, a...
Computer methods and programs in biomedicine
Aug 28, 2024
BACKGROUND AND OBJECTIVE: Tendon segmentation is crucial for studying tendon-related pathologies like tendinopathy, tendinosis, etc. This step further enables detailed analysis of specific tendon regions using automated or semi-automated methods. Thi...
Gait analysis systems are critical for assessing motor function in rehabilitation and elderly care. This study aimed to develop and optimize an abnormal gait classification algorithm considering joint impairments using inertial measurement units (IMU...
This work proposed a liver cancer classification scheme that includes Preprocessing, Feature extraction, and classification stages. The source images are pre-processed using Gaussian filtering. For segmentation, this work proposes a LUV transformatio...
CPT: pharmacometrics & systems pharmacology
Aug 26, 2024
This study addresses the critical issue of drug-induced torsades de pointes (TdP) risk assessment, a vital aspect of new drug development due to its association with arrhythmia and sudden cardiac death. Existing methodologies, particularly those reli...
BACKGROUND: While patients affected by mild cognitive impairment (MCI) exhibit characteristic voxel-mirrored homotopic connectivity (VMHC) alterations, the ability of such VMHC abnormalities to predict the diagnosis of MCI in these patients remains u...
Journal of neurological surgery. Part A, Central European neurosurgery
Aug 23, 2024
BACKGROUND:  Symptomatic cerebral vasospasms are deleterious complication of the rupture of a cerebral aneurysm and potentially lethal. The existing scales used to classify the initial presentation of a subarachnoid hemorrhage (SAH) offer a blink of ...
This article introduces a fast fractal method for classifying breast cancerous lesions in mammography. While fractal methods are valuable for extracting information, they often come with a high computational load and time consumption. This paper demo...