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Systems Integration

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Building integrated ontological knowledge structures with efficient approximation algorithms.

BioMed research international
The integration of ontologies builds knowledge structures which brings new understanding on existing terminologies and their associations. With the steady increase in the number of ontologies, automatic integration of ontologies is preferable over ma...

Semantic Web Ontology and Data Integration: a Case Study in Aiding Psychiatric Drug Repurposing.

Studies in health technology and informatics
There remain significant difficulties selecting probable candidate drugs from existing databases. We describe an ontology-oriented approach to represent the nexus between genes, drugs, phenotypes, symptoms, and diseases from multiple information sour...

Application of hierarchical dissociated neural network in closed-loop hybrid system integrating biological and mechanical intelligence.

PloS one
Neural networks are considered the origin of intelligence in organisms. In this paper, a new design of an intelligent system merging biological intelligence with artificial intelligence was created. It was based on a neural controller bidirectionally...

Slithering towards autonomy: a self-contained soft robotic snake platform with integrated curvature sensing.

Bioinspiration & biomimetics
Soft robotic snakes promise significant advantages in achieving traveling curvature waves with a reduced number of active segments as well as allowing for safe and adaptive interaction with the environment and human users. However, current soft robot...

Situated Agents and Humans in Social Interaction for Elderly Healthcare: From Coaalas to AVICENA.

Journal of medical systems
Assistive Technologies (AT) are an application area where several Artificial Intelligence techniques and tools have been successfully applied to support elderly or impeded people on their daily activities. However, approaches to AT tend to center in ...

LedPred: an R/bioconductor package to predict regulatory sequences using support vector machines.

Bioinformatics (Oxford, England)
UNLABELLED: Supervised classification based on support vector machines (SVMs) has successfully been used for the prediction of cis-regulatory modules (CRMs). However, no integrated tool using such heterogeneous data as position-specific scoring matri...

KNOWLEDGE-ASSISTED APPROACH TO IDENTIFY PATHWAYS WITH DIFFERENTIAL DEPENDENCIES.

Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing
We have previously developed a statistical method to identify gene sets enriched with condition-specific genetic dependencies. The method constructs gene dependency networks from bootstrapped samples in one condition and computes the divergence betwe...