AIMC Topic: Technology Assessment, Biomedical

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Artificial intelligence in key pricing, reimbursement, and market access (PRMA) processes: better, faster, cheaper-can you really pick two?

Journal of medical economics
The rapid evolution of large language models (LLMs) and machine learning (ML) presents both significant opportunities and challenges for market access processes. These sophisticated AI systems, built on transformer architectures and extensive dataset...

The EU project Real4Reg: unlocking real-world data with AI.

Health research policy and systems
BACKGROUND: The use of real-world data is established in post-authorization regulatory processes such as pharmacovigilance of drugs and medical devices, but is still frequently challenged in the pre-authorization phase of medicinal products. In addit...

ESR Essentials: how to get to valuable radiology AI: the role of early health technology assessment-practice recommendations by the European Society of Medical Imaging Informatics.

European radiology
AI tools in radiology are revolutionising the diagnosis, evaluation, and management of patients. However, there is a major gap between the large number of developed AI tools and those translated into daily clinical practice, which can be primarily at...

Artificial intelligence applied in human health technology assessment: a scoping review protocol.

JBI evidence synthesis
OBJECTIVE: This scoping review aims to map studies that applied artificial intelligence (AI) tools to perform health technology assessment tasks in human health care. The review also aims to understand specific processes in which the AI tools were ap...

R WE ready for reimbursement? A round up of developments in real-world evidence relating to health technology assessment: part 17.

Journal of comparative effectiveness research
In this update, we discuss a position statement from the National Institute of Health and Care Excellence (NICE) on the use of artificial intelligence for evidence generation and publications reviewing the use of real-world data as external control a...

Artificial intelligence for breast cancer detection and its health technology assessment: A scoping review.

Computers in biology and medicine
BACKGROUND: Recent healthcare advancements highlight the potential of Artificial Intelligence (AI) - and especially, among its subfields, Machine Learning (ML) - in enhancing Breast Cancer (BC) clinical care, leading to improved patient outcomes and ...

Health technology assessment framework for artificial intelligence-based technologies.

International journal of technology assessment in health care
OBJECTIVES: Artificial intelligence (AI)-based health technologies (AIHTs) have already been applied in clinical practice. However, there is currently no standardized framework for evaluating them based on the principles of health technology assessme...

Generative Artificial Intelligence for Health Technology Assessment: Opportunities, Challenges, and Policy Considerations: An ISPOR Working Group Report.

Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research
OBJECTIVES: To provide an introduction to the uses of generative artificial intelligence (AI) and foundation models, including large language models, in the field of health technology assessment (HTA).

Automated Mass Extraction of Over 680,000 PICOs from Clinical Study Abstracts Using Generative AI: A Proof-of-Concept Study.

Pharmaceutical medicine
BACKGROUND: Generative artificial intelligence (GenAI) shows promise in automating key tasks involved in conducting systematic literature reviews (SLRs), including screening, bias assessment and data extraction. This potential automation is increasin...

Machine Learning Methods to Estimate Individualized Treatment Effects for Use in Health Technology Assessment.

Medical decision making : an international journal of the Society for Medical Decision Making
BACKGROUND: Recent developments in causal inference and machine learning (ML) allow for the estimation of individualized treatment effects (ITEs), which reveal whether treatment effectiveness varies according to patients' observed covariates. ITEs ca...