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Tissue Donors

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Assessing donor kidney function: the role of CIRBP in predicting delayed graft function post-transplant.

Frontiers in immunology
INTRODUCTION: Delayed graft function (DGF) shortens the survival time of transplanted kidneys and increases the risk of rejection. Current methods are inadequate in predicting DGF. More precise tools are required to assess kidney suitability for tran...

Predicting Donor Selection and Multi-Organ Transplantation within Organ Procurement Organizations Using Machine Learning.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
Organ procurement organizations (OPOs) play a crucial role in the field of organ transplantation, serving as key intermediaries in the process of organ donation. However, despite their vital function, there exists a pressing issue of transparency wit...

Predicting graft and patient outcomes following kidney transplantation using interpretable machine learning models.

Scientific reports
The decision to accept a deceased donor organ offer for transplant, or wait for something potentially better in the future, can be challenging. Clinical decision support tools predicting transplant outcomes are lacking. This project uses interpretabl...

Artificial intelligence-driven automated lung sizing from chest radiographs.

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons
Lung size measurements play an important role in transplantation, as optimal donor-recipient size matching is necessary to ensure the best possible outcome. Although several strategies for size matching are currently used, all have limitations, and n...

An integrated machine learning model enhances delayed graft function prediction in pediatric renal transplantation from deceased donors.

BMC medicine
BACKGROUND: Kidney transplantation is the optimal renal replacement therapy for children with end-stage renal disease; however, delayed graft function (DGF), a common post-operative complication, may negatively impact the long-term outcomes of both t...

Raising awareness may increase the likelihood of hematopoietic stem cell donation: a nationwide survey using artificial intelligence.

International journal of hematology
BACKGROUND: In Italy, the demand for allogeneic transplantation exceeds the number of compatible donors in the Italian Bone Marrow Donor Registry (IBMDR). This study aimed to explore the knowledge, beliefs, opinions, values, and feelings of the Itali...

Improved survival prediction for kidney transplant outcomes using artificial intelligence-based models: development of the UK Deceased Donor Kidney Transplant Outcome Prediction (UK-DTOP) Tool.

Renal failure
The UK Deceased Donor Kidney Transplant Outcome Prediction (UK-DTOP) Tool, developed using advanced artificial intelligence (AI), significantly enhances the prediction of outcomes for deceased-donor kidney transplants in the UK. This study analyzed d...

Artificial Intelligence-Assisted Matching of Human Postmortem Donors to Ocular Research Projects.

Advances in experimental medicine and biology
The scarcity of human ocular samples with short postmortem intervals (PMIs) is a significant issue in ophthalmic research and drug discovery. A contributing factor is that eye banks must manually match donor data to prospective research project crite...

Machine learning enhanced immunologic risk assessments for solid organ transplantation.

Scientific reports
The purpose of this study was to enhance the prediction of solid-organ recipient and donor crossmatch compatibility by applying machine learning (ML). Prediction of crossmatch compatibility is complex and requires an understanding of the recipient an...

Leveraging Artificial Intelligence to Assess Perceived Age and Donor Facial Resemblance After Face Transplantation.

Annals of plastic surgery
PURPOSE: A major concern for patients undergoing facial transplantation relates to postoperative appearance. This study leverages artificial intelligence (AI) visual analysis software to provide an objective assessment of perceived age and degree of ...