AIMC Topic: Tissue Engineering
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Ultrasound-activated piezoelectric biomaterials for cartilage regeneration.
Ultrasonics sonochemistry
Apr 14, 2025
Due to the low density of chondrocytes and limited ability to repair damaged extracellular matrix (ECM) in cartilage, many patients with congenital or acquired craniofacial trauma require filler graft materials to support facial structure, restore fu...
Soft Biological Actuators for Meter-Scale Homeostatic Biohybrid Robots.
Chemical reviews
Mar 26, 2025
Skeletal muscle's elegant protein-based architecture powers motion throughout the animal kingdom, with its constituent actomyosin complexes driving intra- and extra-cellular motion. Classical motors and recently developed soft actuators cannot match ...
Innovative construction and application of bile duct organoids: Unraveling the complexity of bile duct diseases and potential therapeutic strategies.
Cancer letters
Mar 10, 2025
The biliary system is crucial for liver function, regulating bile production, secretion, and transport. Dysfunctions within this system can lead to various diseases, such as cholangiopathies and biliary fibrosis, which may progress from benign to mal...
Predicting inflammatory response of biomimetic nanofibre scaffolds for tissue regeneration using machine learning and graph theory.
Journal of materials chemistry. B
Mar 5, 2025
Tissue regeneration after a wound occurs through three main overlapping and interrelated stages namely inflammatory, proliferative, and remodelling phases, respectively. The inflammatory phase is key for successful tissue reconstruction and triggers ...
Advancing regenerative medicine: the Aceman system's pioneering automation and machine learning in mesenchymal stem cell biofabrication.
Biofabrication
Feb 27, 2025
Mesenchymal stem cells (MSCs) are pivotal in advancing regenerative medicine; however, the large-scale production of MSCs for clinical applications faces significant challenges related to efficiency, cost, and quality assurance. We introduce the Auto...
Bioinspired design of a tissue-engineered ray with machine learning.
Science robotics
Feb 12, 2025
In biomimetic design, researchers recreate existing biological structures to form functional devices. For biohybrid robotic swimmers assembled with tissue engineering, this is problematic because most devices operate at different length scales than t...
Design and optimization of tamarind seed polysaccharide-based scaffold for tissue engineering applications using statistical modeling and machine learning, and it's in-vitro validation.
International journal of biological macromolecules
Jan 30, 2025
This study explores the development and optimization of a novel biomaterial scaffold for tissue engineering, composed of Tamarind seed polysaccharide (TSP), Hydroxypropyl methylcellulose (HPMC), Chitosan (CS), and Sodium alginate (ALG). Scaffold prop...
Harnessing machine learning algorithms for the prediction and optimization of various properties of polylactic acid in biomedical use: a comprehensive review.
Biomedical materials (Bristol, England)
Jan 22, 2025
Machine learning (ML) has emerged as a transformative tool in various industries, driving advancements in key tasks like classification, regression, and clustering. In the field of chemical engineering, particularly in the creation of biomedical devi...
A spatiotemporal and machine-learning platform facilitates the manufacturing of hPSC-derived esophageal mucosa.
Developmental cell
Jan 10, 2025
Human pluripotent stem cell-derived tissue engineering offers great promise for designer cell-based personalized therapeutics, but harnessing such potential requires a deeper understanding of tissue-level interactions. We previously developed a cell ...
Optimizing the value of bioinks and robotics to advance in vivo bioprinting.
Current opinion in biotechnology
Jan 9, 2025
In vivo bioprinting strategies aim at facilitating immediate integration of engineered tissues with the host's biological system. As integral parts of current bioprinting technologies, bioinks and robotics should be holistically considered for new bi...
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