The Food and Drug Administration's recent decision to eliminate mandatory animal testing for drug approval marks a significant shift to alternative methods. Similarly, the European Parliament is advocating for a faster transition, reflecting public p...
Freeze casting, a manufacturing technique widely applied in biomedical fields for fabricating biomaterial scaffolds, poses challenges for predicting directional solidification due to its highly nonlinear behavior and complex interplay of process para...
The myotendinous junction (MTJ) facilitates force transmission between muscle and tendon to produce joint movement. The complex microarchitecture and regional mechanical heterogeneity of the myotendinous junction pose major challenges in creating thi...
Biofabrication is an advanced technology that holds great promise for constructing highly biomimeticthree-dimensional human organs. Such technology would help address the issues of immune rejection and organ donor shortage in organ transplantation, a...
Cardiac screening of newly discovered drugs remains a longstanding challenge for the pharmaceutical industry. While therapeutic efficacy and cardiotoxicity are evaluated through preclinical biochemical and animal testing, 90 % of lead compounds fail ...
International journal of biological macromolecules
39667472
Polymeric hydrogels, characterized by their highly hydrophilic three-dimensional network structures, boast exceptional physical and chemical properties alongside high biocompatibility and biodegradability. These attributes make them indispensable in ...
Despite the widespread popularity of the "scratch assay," where a pipette is dragged manually through cultured tissue to create a gap to study cell migration and healing, it carries significant drawbacks. Its heavy reliance on manual technique can co...
The emergence of Artificial Intelligence (AI) and its usage in regenerative medicine represents a significant opportunity that holds the promise of tackling critical challenges and improving therapeutic outcomes. This article examines the ways in whi...
Biohybrid micro/nanorobots hold a great potential for advancing biomedical research. These tiny structures, designed to mimic biological organisms, offer a promising method for targeted drug delivery, tissue engineering, biosensing/imaging, and cance...
Machine learning (ML) has emerged as a transformative tool in various industries, driving advancements in key tasks like classification, regression, and clustering. In the field of chemical engineering, particularly in the creation of biomedical devi...