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Development and validation of MRI-based deep learning models for prediction of microsatellite instability in rectal cancer.
Cancer medicine
May 8, 2021
BACKGROUND: Microsatellite instability (MSI) predetermines responses to adjuvant 5-fluorouracil and immunotherapy in rectal cancer and serves as a prognostic biomarker for clinical outcomes. Our objective was to develop and validate a deep learning m...
An artificial intelligence algorithm for analyzing acetaminophen-associated toxic hepatitis.
Human & experimental toxicology
May 6, 2021
INTRODUCTION: Very little artificial intelligence (AI) work has been performed to investigate acetaminophen-associated hepatotoxicity. The objective of this study was to develop an AI algorithm for analyzing weighted features for toxic hepatitis afte...
Chronic cholestasis detection by a novel tool: automated analysis of cytokeratin 7-stained liver specimens.
Diagnostic pathology
May 6, 2021
BACKGROUND: The objective was to build a novel method for automated image analysis to locate and quantify the number of cytokeratin 7 (K7)-positive hepatocytes reflecting cholestasis by applying deep learning neural networks (AI model) in a cohort of...
Artificial intelligence-enabled electrocardiograms for identification of patients with low ejection fraction: a pragmatic, randomized clinical trial.
Nature medicine
May 6, 2021
We have conducted a pragmatic clinical trial aimed to assess whether an electrocardiogram (ECG)-based, artificial intelligence (AI)-powered clinical decision support tool enables early diagnosis of low ejection fraction (EF), a condition that is unde...
Machine learning of EEG spectra classifies unconsciousness during GABAergic anesthesia.
PloS one
May 6, 2021
In current anesthesiology practice, anesthesiologists infer the state of unconsciousness without directly monitoring the brain. Drug- and patient-specific electroencephalographic (EEG) signatures of anesthesia-induced unconsciousness have been identi...
Detection of Postural Control in Young and Elderly Adults Using Deep and Machine Learning Methods with Joint-Node Plots.
Sensors (Basel, Switzerland)
May 5, 2021
Postural control decreases with aging. Thus, an efficient and accurate method of detecting postural control is needed. We enrolled 35 elderly adults (aged 82.06 ± 8.74 years) and 20 healthy young adults (aged 21.60 ± 0.60 years) who performed standin...
Pain Assessment Tool With Electrodermal Activity for Postoperative Patients: Method Validation Study.
JMIR mHealth and uHealth
May 5, 2021
BACKGROUND: Accurate, objective pain assessment is required in the health care domain and clinical settings for appropriate pain management. Automated, objective pain detection from physiological data in patients provides valuable information to hosp...
The persuasive power of robot touch. Behavioral and evaluative consequences of non-functional touch from a robot.
PloS one
May 5, 2021
The unique physical embodiment of robots enables physical contact between machines and humans. Since interpersonal touch research has demonstrated that touch has several positive behavioral (e.g., reduced stress, better immune functioning) as well as...
Assessment of an AI Aid in Detection of Adult Appendicular Skeletal Fractures by Emergency Physicians and Radiologists: A Multicenter Cross-sectional Diagnostic Study.
Radiology
May 4, 2021
Background The interpretation of radiographs suffers from an ever-increasing workload in emergency and radiology departments, while missed fractures represent up to 80% of diagnostic errors in the emergency department. Purpose To assess the performan...
Humans
Radiographic Image Interpretation, Computer-Assisted
Adult
Sensitivity and Specificity
Cross-Sectional Studies
Male
Reproducibility of Results
Aged
Fractures, Bone
Aged, 80 and over
Emergency Service, Hospital
Young Adult
Radiologists
Middle Aged
Artificial Intelligence
Adolescent
Physicians
Retrospective Studies
Female
Application of machine learning to predict reduction in total PANSS score and enrich enrollment in schizophrenia clinical trials.
Clinical and translational science
May 3, 2021
Clinical trial efficiency, defined as facilitating patient enrollment, and reducing the time to reach safety and efficacy decision points, is a critical driving factor for making improvements in therapeutic development. The present work evaluated a m...
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