Latest AI and machine learning research in allergy for healthcare professionals.
Despite advancements in therapeutic cancer vaccines, clinical translation has been hindered by limited efficacy, with Sipuleucel-T remaining the only FDA-approved therapeutic cancer vaccine to date. However, recent advances in personalized mRNA vaccines, such as Moderna's mRNA-4157 and BioNTech's autogene cevumeran, have demonstrated significant reductions in recurrence risk and improved survival ...
OBJECTIVE: Automating administrative tasks, such as compiling a patient's medical history, could help general practitioners in their daily work. AI performance has improved in recent decades, but skepticism among professionals limits its use in medical practice, due to fears of gaps and biases. This study attempts to evaluate the effectiveness of AI in recording patient histories compared to gener...
Keratins (KRTs) are intermediate filament proteins expressed in epithelial cells and serve as diagnostic cancer biomarkers. They serve pivotal roles i...
Atopic dermatitis (AD) is a chronic, multifactorial inflammatory skin disease with a complex, heterogeneous pathogenesis. Understanding its mechanisms...
Assessing venous thromboembolism (VTE) risk after immunotherapy remains important for lung cancer management. We analyzed 2,300 patients receiving fir...
Immunotherapy has revolutionized the treatment landscape of breast cancer, particularly for triple-negative breast cancer (TNBC), yet primary and acqu...
BACKGROUND: EphrinB2 and its receptor EphB4 have been reported to play a crucial role in the development of the cardiovascular system, and the process...
Mechanisms of neurotransmitter detection using a two-dimensional MoS2 platform are discussed. Machine learning methods are applied to distinguish the ...
BACKGROUND: Multiple programmed cell death (PCD) modalities, including apoptosis, autophagy, and ferroptosis, are closely implicated in spontaneous pr...
Cow's milk-specific IgE (sIgE) is a crucial serum biomarker for cow's milk allergy (CMA) in children. However, its low abundance and the scarcity of r...
BACKGROUND: Hypersensitivity pneumonitis (HP) manifests as fibrotic (FHP) and non-fibrotic (NFHP) phenotypes. Clinically distinguishing FHP from idiop...
BACKGROUND: Postoperative pulmonary infection (PPI) is a common and serious complication in older adults undergoing hip fracture surgery, leading to p...
Cancer vaccines are an attractive immunotherapeutic approach, and numerous clinical trials are ongoing. However, most candidates have not achieved sta...
The ability to predict T-cell receptor (TCR) specificity from sequences could transform immunotherapy, vaccine development, and our understanding of i...
Although diffuse large B-cell lymphoma (DLBCL) is a heterogeneous disease, existing prognostic tools, including the revised International Prognostic I...
Uveal melanoma is the most frequent primary intraocular malignancy in adults and is characterized by an aggressive clinical course, high propensity fo...
Gastric cancer (GC) shows strong biological heterogeneity and frequent disruption of inflammatory and metabolic programs, which affect tumor progressi...
PURPOSE: Muscle-invasive bladder cancer (MIBC) remains biologically heterogeneous, and clinicopathological variables do not fully capture epithelial-s...
Non-small cell lung cancer (NSCLC) is the most common cancer-related cause of death among all countries globally, mostly because of late diagnosis, he...
BACKGROUND: Head and neck squamous cell carcinomas (HNSCCs) cause considerable morbidity and mortality. Multimodal treatment strategies can cause sign...