Atherosclerosis

Multicenter External Validation of an AI-Based Funduscopic Carotid Atherosclerosis Score and Assessment of Its Association With Coronary Artery Calcification: External Validation Study.

BACKGROUND: Screening for atherosclerosis is essential for early intervention, but conventional scre...

MACHINE LEARNING VERSUS PENALISED LOGISTIC REGRESSION FOR PREDICTING IN-HOSPITAL MORTALITY IN RUPTURED ABDOMINAL AORTIC ANEURYSM: A COMPARISON USING A UNIFORM VALIDATION FRAMEWORK.

BACKGROUND: Ruptured abdominal aortic aneurysm (rAAA) remains associated with substantial in-hospita...

Digital Oral Health beyond Professional Dental Care Settings: A Scoping Review of Technologies and Applications from Prevention to Early Detection.

BACKGROUND: Oral non-communicable diseases impose a substantial and unequally distributed global bur...

Macrophage Lipid Homeostasis Drives IVDD via a Senescence-Dependent Impairment of Efferocytosis.

Intervertebral disc degeneration (IVDD) is a major contributor to low back pain, but the immune-meta...

CASP1 as a key autophagy-related gene in atherosclerosis: Identification by bioinformatics analysis and experimental validation.

OBJECTIVE: This study identified potential autophagy-related genes (ARGs) in atherosclerosis using b...

Artificial intelligence-enhanced management system for secondary prevention of coronary heart disease: a randomized clinical trial.

BACKGROUND: Secondary prevention of coronary heart disease (CHD) remains suboptimal due to fragmente...

VCAM-1 Serves as a Biomarker for Discriminating Eosinophilic CRSwNP and Regulates IL-13-Induced Vascular Remodeling.

BackgroundChronic rhinosinusitis with nasal polyps (CRSwNP) is a highly heterogeneous inflammatory d...

Short-interval coronary plaque remodeling assessed by serial AI-quantified coronary CTA during intensive plaque-directed therapy.

Linking Metabolic Subgroups and Adverse Pregnancy Outcomes in GDM: A Complementary Analytic Approach of Logistic Regressions and Machine Learning.

AIMS: Associations between metabolic heterogeneity in women with gestational diabetes mellitus (GDM)...

Microfluidic Chip Platforms for Red Blood Cell Storage Lesion Quality Control and Precision Transfusion.

Red blood cell (RBC) transfusion is a core clinical intervention. However, hypothermic storage induc...

Comparative analysis of machine learning techniques for cardiovascular disease prediction.

BACKGROUND AND OBJECTIVES: Early and accurate prediction of cardiovascular disease (CVD) is fundamen...

CKLF1 Serves as a Pivotal Mediator of Blood-Brain Barrier Disruption and Neuroinflammation via PI3K/AKT/mTOR Signaling in Ischemic Stroke.

Ischemic stroke (IS) is accompanied by blood-brain barrier (BBB) disruption and neuroinflammatory ac...

Development of machine learning-based predictive models for evaluating risk in the contralateral ear among patients with unilateral sudden sensorineural hearing loss.

BACKGROUND: Sequential bilateral sudden sensorineural hearing loss (Se-BSSHL) may occur after an ini...

SPCC: Inferring Spatial Cell-Cell Interaction by Integrating Single-cell and Spatial Transcriptomics.

Study of single-cell spatial biology reveals the importance of integrating single-cell and spatial d...

Computational wireless indices for the assessment of myocardial ischaemia.

The assessment of myocardial ischaemia is entering a new computational era. Beyond the traditional b...

Artificial Intelligence-Assisted Contrast-Enhanced Ultrasound for Perfusion Evaluation: State-of-the-Art Review.

Accurate perfusion evaluation is crucial for clinical diagnosis and treatment, such as lesion charac...

Identification of Erectile Dysfunction From Routine Blood Test Data: Development and Validation of a Machine Learning-Based Prediction Model.

BACKGROUND: Erectile dysfunction (ED) is a prevalent male health disorder and a recognized sentinel ...

Precision Lipid Management in the Era of Biotechnology and Artificial Intelligence: From Gene Editing to Smart Drug Delivery.

BACKGROUND: Hyperlipidemia is a major modifiable contributor to atherosclerotic cardiovascular disea...

Topical exposure to di(2-ethylhexyl) phthalate aggravates atopic dermatitis: an integrated network toxicology, bioinformatics, and experiment analysis.

Di(2-ethylhexyl) phthalate (DEHP) is one of the most widely used plasticizers; however, whether cuta...

A novel adrenomedullin receptor signaling-based prognostic model predicts immunosuppressive microenvironment and informs therapeutic stratification in hepatocellular carcinoma: A retrospective bioinformatics study.

The adrenomedullin receptor signaling pathway plays a crucial role in tumor progression, yet its com...

Spatial decoupling of plaque and circulating immune programs defines a robust gene signature in atherosclerosis: A multi-cohort integrative analysis.

Atherosclerosis (AS) is driven by chronic vascular inflammation, yet the relationship between immune...