Bacterial Infection

A Deep Neural Network Framework for the Detection of Bacterial Diseases from Chest X-Ray Scans.

AIMS: This research aims to develop an advanced deep-learning framework for detecting respiratory diseases, including COVID-19, pneumonia, and tuberculosis (TB), using chest X-ray scans.

Optimizing phage therapy with artificial intelligence: a perspective.

Phage therapy is emerging as a promising strategy against the growing threat of antimicrobial resistance, yet phage and bacteria are incredibly diverse and idiosyncratic in their interactions with one another. Clinical applications of phage therapy often rely on a process of manually screening collections of naturally occurring phages for activity against a specific clinical isolate of bacteria, a...

Risk-reward trade-off during carbon starvation generates dichotomy in motility endurance among marine bacteria.

Copiotrophic marine bacteria contribute to the control of carbon storage in the ocean by remineralizing organic matter. Motility presents copiotrophs ...

Multi-Omics Analysis of the virulence factors and designing of next-generation multi-epitopes Vaccines against Rickettsia prowazekii: a computer-aided vaccine designing approach.

Rickettsia is a genus of bacteria that are obligate intracellular parasites and are responsible for the febrile diseases known collectively as Rickett...

Deep learning-based framework for Mycobacterium tuberculosis bacterial growth detection for antimicrobial susceptibility testing.

Tuberculosis (TB) kills more people annually than any other pathogen. Resistance is an ever-increasing global problem, not least because diagnostics r...

Synergistic potential of halophytes and halophilic/halotolerant plant growth-promoting bacteria in saline soil remediation: Adaptive mechanisms, challenges, and sustainable solutions.

Salinity stress poses significant challenges to agriculture, reducing productivity and limiting arable land by causing ionic and osmotic imbalances in...

Paper-based SERS chip with adaptive attention neural network for pathogen identification.

High-speed and accuracy identification of pathogens has become increasingly critical in both individual patient care and public health. Artificial int...

Challenges and Opportunities: Interplay between Infectious Disease and Antimicrobial Resistance in Medical Device Surface Applications.

Antimicrobial resistance (AMR) is a growing silent pandemic driven by multidrug-resistant infections, particularly those associated with medical devic...

Combatting with β-Lactam Antibiotics: A Revived Weapon?

is a significant threat to public health as an aggressive, opportunistic pathogen. The use of β-lactam antibiotics such as penicillins, cephalosporin...

Multiobjective learning and design of bacteriophage specificity.

To better understand and design proteins, it is crucial to consider the multifunctional landscapes on which all proteins exist. Proteins are often opt...

Seasonal total coliform dynamics in a drinking water reservoir.

Maintaining high-quality drinking water supply reservoirs is important for protecting public health. Despite extensive watershed protection efforts, r...

Discrimination of Respiratory Tract Infections by a Reduced Graphene Oxide Array Modified with Metal-Organic Frameworks and Metal Phthalocyanines.

As a prevalent clinical condition, it is critical to distinguish between bacterial and viral respiratory tract infections given their pivotal role in ...

De Novo Design of Highly Stable Binders Targeting Dihydrofolate Reductase in Klebsiella pneumoniae.

The study aims to design novel therapeutic inhibitors targeting the DHFR protein of Klebsiella pneumoniae. However, challenges like bacterial resistan...

Distinguishing critical microbial community shifts from normal temporal variability in human and environmental ecosystems.

Differentiating significant microbial community changes from normal fluctuations is vital for understanding microbial dynamics in human and environmen...

Coumarin hybrids: dual-target candidates for future antimicrobial and antitubercular therapies.

AIMS: This study aimed to synthesize, characterize, and evaluate the antimicrobial and antitubercular activities of two novel series of coumarin-based...

Secretions Induce Shifts in Macrolactin Composition and Reduction in Antimicrobial Activity of BNC5.

, a pathogen causing bacterial wilt, threatens global crop production, necessitating sustainable biocontrol solutions. is a promising biocontrol agen...

Optimization of process conditions and kinetic microbial growth for milk fermentation using domestic kefir grains from Costa Rica.

Kefir, a fermented milk product, differs from yogurt due to its unique microbial composition, offering a broad spectrum of health benefits. Given its ...

Antibacterial and Antibiofilm Activities of Colistin and Ceftazidime-Avibactam Conjugated Silver Nanoparticles.

Multidrug-resistant (MDR) Gram-negative bacteria constitute a major global health concern, and the increasing resistance to last-line antimicrobial ag...

AgNPs@Tea Polyphenol-Poly(acrylic acid) Hydrogel Dressing with Synergistic Antibacterial Action and Low Cytotoxicity.

Bacterial infections pose a severe threat to human health, and excessive antibiotic use induces bacterial resistance. Although silver-containing nanop...

Variations of the chemical components and biological activities of Thymus capitatus essential oil from three regions in Palestine.

Thymus capitatus is a widely utilized medicinal plant in Palestine. The main goal of this study was to assess the phytochemical content of T. capitatu...